Literature DB >> 858372

Differential effects of opiates on the incorporation of [14C] thiamine in the central nervous system of the rat.

A L Misra, N L Vadlamani, R B Pontani.   

Abstract

Opiate agonist (morphine), pure antagonist (naloxone), mixed agonist-antagonist (nalorphine) and analgesically inactive enantiomorph (dextrorphan) produced differential stereoselective effects on the incorporation of [14C] thiamine in the central nervous system of the rats. The possible role of thiamine in opiate effects and its implications are discussed.

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Year:  1977        PMID： 858372     DOI： 10.1007/BF02002834

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Proceedings: Morphine analgesia-its main site of action?

Authors:  P K Dey; W Feldberg
Journal:  J Physiol       Date:  1975-06       Impact factor: 5.182

2.  Influence of cocarboxylase on tolerance to morphine in the rat.

Authors:  L ANGELUCCI
Journal:  Nature       Date:  1958-04-05       Impact factor: 49.962

3.  Morphine induced calcium depletion in discrete regions of rat brain.

Authors:  H L Cardenas; D H Ross
Journal:  J Neurochem       Date:  1975-03       Impact factor: 5.372

4.  Persistence of methadone-3H and metabolite in rat brain after a single injection and its implications on pharmacological tolerance.

Authors:  A L Misra; S J Mulé
Journal:  Nature       Date:  1972-07-21       Impact factor: 49.962

5.  Pharmacokinetics and metabolism of (3H) thebaine.

Authors:  A L Misra; R B Pontani; S J Mulé
Journal:  Xenobiotica       Date:  1974-01       Impact factor: 1.908

6.  Persistence of morphine in central nervous system of rats after a singel injection and its bearing on tolerance.

Authors:  A L Misra; C L Mitchell; L A Woods
Journal:  Nature       Date:  1971-07-02       Impact factor: 49.962

7.  Physiological disposition and metabolism of levo-methadone-1- 3 H in nontolerant and tolerant rats.

Authors:  A L Misra; S J Mulé; R Bloch; N L Vadlamani
Journal:  J Pharmacol Exp Ther       Date:  1973-05       Impact factor: 4.030

8.  Ion movements and thiamine. II. The release of the vitamin from membrane fragments.

Authors:  Y Itokawa; J R Cooper
Journal:  Biochim Biophys Acta       Date:  1970

9.  Analgesia from electrical stimulation in the brainstem of the rat.

Authors:  D J Mayer; T L Wolfle; H Akil; B Carder; J C Liebeskind
Journal:  Science       Date:  1971-12-24       Impact factor: 47.728

10.  TRANSPORT AND METABOLISM OF THIAMINE IN RAT BRAIN CORTEX IN VITRO.

Authors:  S K SHARMA; J H QUASTEL
Journal:  Biochem J       Date:  1965-03       Impact factor: 3.857
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