| Literature DB >> 858293 |
Abstract
The action of intravenously administered diazepam (Valium) on postsynaptic inhibition was studied in cat motor cortex. The efficacy of postsynaptic inhibition of pyramidal tract cells was measured as the ability to suppress action potential generation. Diazepam increased the suppression of action potentials by inhibition. This effect may explain the anticonvulsant action of diazepam.Entities:
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Year: 1977 PMID： 858293 DOI： 10.1111/j.1528-1157.1977.tb05594.x
Source DB: PubMed Journal: Epilepsia ISSN： 0013-9580 Impact factor: 5.864