Literature DB >> 8580447

Micrographia in Parkinson's disease.

J L Contreras-Vidal1, H L Teulings, G E Stelmach.   

Abstract

A computational neural model of movement production in normal and Parkinson's disease (PD) is used to provide a neural account for the source of micrographia in PD handwriting. It is hypothesized that smaller than normal pallido-thalamic signals, due to dopamine depletion, are responsible for the observed overall smallness, slowness and variability in PD handwriting. Experimental data from PD patients that show micrographia support this hypothesis and imply the functional segregation of basal ganglia neural populations.

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Year:  1995        PMID： 8580447     DOI： 10.1097/00001756-199510010-00032

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  8 in total

1.  Discrete and dynamic scaling of the size of continuous graphic movements of parkinsonian patients and elderly controls.

Authors:  M G Longstaff; P R Mahant; M A Stacy; A W A Van Gemmert; B C Leis; G E Stelmach
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-03       Impact factor: 10.154

2.  Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia?

Authors:  Christian Blahak; Hans-Holger Capelle; Hansjoerg Baezner; Thomas M Kinfe; Michael G Hennerici; Joachim K Krauss
Journal:  J Neural Transm (Vienna)       Date:  2011-01-19       Impact factor: 3.575

3.  Altered aiming movements in Parkinson's disease patients and elderly adults as a function of delays in movement onset.

Authors:  Diana H Romero; Arend W A Van Gemmert; Charles H Adler; Harold Bekkering; George E Stelmach
Journal:  Exp Brain Res       Date:  2003-06-03       Impact factor: 1.972

4.  Increased periodontal pathology in Parkinson's disease.

Authors:  Johannes Schwarz; Engelbert Heimhilger; Alexander Storch
Journal:  J Neurol       Date:  2006-03-06       Impact factor: 4.849

5.  Parkinson's disease patients undershoot target size in handwriting and similar tasks.

Authors:  A W A Van Gemmert; C H Adler; G E Stelmach
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-11       Impact factor: 10.154

6.  Biased wrist and finger coordination in Parkinsonian patients during performance of graphical tasks.

Authors:  Natalia Dounskaia; Arend W A Van Gemmert; Berta C Leis; George E Stelmach
Journal:  Neuropsychologia       Date:  2009-05-04       Impact factor: 3.139

Review 7.  Handwriting Analysis in Parkinson's Disease: Current Status and Future Directions.

Authors:  Mathew Thomas; Abhishek Lenka; Pramod Kumar Pal
Journal:  Mov Disord Clin Pract       Date:  2017-11-01

8.  Biometric handwriting analysis to support Parkinson's Disease assessment and grading.

Authors:  Giacomo Donato Cascarano; Claudio Loconsole; Antonio Brunetti; Antonio Lattarulo; Domenico Buongiorno; Giacomo Losavio; Eugenio Di Sciascio; Vitoantonio Bevilacqua
Journal:  BMC Med Inform Decis Mak       Date:  2019-12-12       Impact factor: 2.796
  8 in total

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