| Literature DB >> 8577258 |
D Georgellis1, B Sohlberg, F U Hartl, A von Gabain.
Abstract
An RNA-binding activity has been identified in Escherichia coli that provides physical protection of RNA against ribonucleases in an ATP- and Mg(2+)-dependent manner. This binding activity is stimulated under growth conditions known to cause a decrease in the rate of mRNA decay. RNA protection is mediated by a protein complex that contains a modified form of the chaperonin GroEL as an indispensable constituent. These results suggest a new role for GroEL as an RNA chaperone.Entities:
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Year: 1995 PMID： 8577258 DOI： 10.1111/j.1365-2958.1995.tb02347.x
Source DB: PubMed Journal: Mol Microbiol ISSN： 0950-382X Impact factor: 3.501