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Literature DB >> 8575879

The structural basis of nuclear function.

Abstract

Most models for transcription and replication involve polymerases that track along the template. We review here experiments that suggest an alternative in which polymerization occurs as the template slides past a polymerase fixed to a large structure in the eukaryotic nucleus--a "factory" attached to a nucleoskeleton. This means that higher-order structure dictates how and when DNA is replicated or transcribed.

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Year: 1995 PMID： 8575879 DOI： 10.1016/s0074-7696(08)61230-9

Source DB: PubMed Journal: Int Rev Cytol ISSN： 0074-7696

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Cited

24 in total

1. Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination.

Authors: X P Zhong; J Carabaña; M S Krangel
Journal: Proc Natl Acad Sci U S A Date: 1999-10-12 Impact factor: 11.205

Review 2. Comparative genome organization in plants: from sequence and markers to chromatin and chromosomes.

Authors: J S Heslop-Harrison
Journal: Plant Cell Date: 2000-05 Impact factor: 11.277

3. Phi29 family of phages.

Authors: W J Meijer; J A Horcajadas; M Salas
Journal: Microbiol Mol Biol Rev Date: 2001-06 Impact factor: 11.056

4. Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration.

Authors: Apolinar Maya-Mendoza; Rolando Hernández-Muñoz; Patricio Gariglio; Armando Aranda-Anzaldo
Journal: Nucleic Acids Res Date: 2003-11-01 Impact factor: 16.971

The structural basis of nuclear function.

1. Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination.

Review 2. Comparative genome organization in plants: from sequence and markers to chromatin and chromosomes.

3. Phi29 family of phages.

4. Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration.

5. A cotranscriptional model for 3'-end processing of the Saccharomyces cerevisiae pre-ribosomal RNA precursor.

6. Functional structure of the cell nucleus.

Review 7. Chromatin domains and nuclear compartments: establishing sites of gene expression in eukaryotic nuclei.

Review 8. A requiem to the nuclear matrix: from a controversial concept to 3D organization of the nucleus.

9. HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions.

10. AAGAG repeat RNA is an essential component of nuclear matrix in Drosophila.