Literature DB >> 8574072

Inhibition of bacterial growth in vitro by human ejaculate seminal plasma fraction 1 and its possible practical use in male infertility phenomenon.

Z H Marcus1, L M Lewin, R Ginsberg.   

Abstract

PURPOSE: The in vitro bacteriostatic effect on bacteria by a fraction of pan class="Species">human ejaculate (HuSePl-Fr1) was studied.
METHOD: As bacterial indicators, Pseudomonas aeruginosa (Pa), total coliforms (Tc), fecal coliforms (Fc), Escherichia coli (Ec), and Staphylococcus aureus (Sa) were used. These bacterial strains are known as agents that cause urinary and sexually transmitted infections (STI).
RESULTS: Preliminary results suggest that HuSePl-Fr1 has a significant in vitro bacteriostatic effect on Pa and Sa at 42 degrees C. In addition, Pa was inhibited at 37 degrees C after 48 hr incubation. The remaining bacterial indicators were not affected.
CONCLUSION: The results indicate a possible protective role of HuSePl-Fr1 in treatment of infertile men due to genital infections.

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Year:  1995        PMID: 8574072     DOI: 10.1007/bf02211145

Source DB:  PubMed          Journal:  J Assist Reprod Genet        ISSN: 1058-0468            Impact factor:   3.412


  8 in total

1.  Preparation of sperm-free seminal plasma from human semen.

Authors:  E W Jecht; C H Poon
Journal:  Fertil Steril       Date:  1975-01       Impact factor: 7.329

2.  In vitro studies in reproductive immunology: 4. Mechanisms of immune response control in human male genital tract.

Authors:  Z H Marcus; E V Hess; J H Freisheim
Journal:  Int J Fertil       Date:  1983

3.  In vitro studies in reproductive immunology. 1. Suppression of cell-mediated immune response by human spermatozoa and fractions isolated from human seminal plasma.

Authors:  Z H Marcus; J H Freisheim; J L Houk; J H Herman; E V Hess
Journal:  Clin Immunol Immunopathol       Date:  1978-03

4.  In vitro studies in reproductive immunology. - 2. Demonstration of the inhibitory effect of male genital tract constituents on PHA-stimulated mitogenesis and E-rosette formation of human lymphocytes.

Authors:  Z H Marcus; E V Hess; J H Herman; P Troiano; J Freisheim
Journal:  J Reprod Immunol       Date:  1979-07       Impact factor: 4.054

5.  Studies on immune infertility: a hypothesis on the etiology of immune infertility based on the biological role of seminal plasma immune response inhibitor.

Authors:  C Prakash; R W Lang
Journal:  Mt Sinai J Med       Date:  1980 Sep-Oct

6.  The inhibitors in seminal plasma.

Authors:  E V Hess; Z H Marcus
Journal:  J Lab Clin Med       Date:  1980-10

7.  Immunosuppressive activity and polyamine levels of seminal plasma in azo-ospermic, oligospermic, and normospermic men.

Authors:  B Shohat; R Maayan; R Singer; M Sagiv; H Kaufman; Z Zukerman
Journal:  Arch Androl       Date:  1990

8.  Membrane filtration differentiation of E. coli from coliforms in the examination of water.

Authors:  A Mates; M Shaffer
Journal:  J Appl Bacteriol       Date:  1989-09
  8 in total

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