Literature DB >> 8573714

Breast cancer and importance of zygosity determination in triplet sisters.

H T Lynch1, P Watson, T Conway, J Lynch, J Boyd.   

Abstract

This study is the first to examine the genetic risk in a breast cancer-prone family wherein two of three triplet sisters and their mother manifested breast cancer. The unaffected triplet, the proband, was found to be monozygotic with her deceased sister through DNA testing of tumor blocks and dizygotic to her living affected sister. Genetic counseling implications are discussed.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 8573714     DOI： 10.1007/bf00713403

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  8 in total

1.  CONCORDANT DISEASE IN IDENTICAL TWINS.

Authors:  W D HEIZER; E F LEWISON
Journal:  JAMA       Date:  1964-04-20       Impact factor: 56.272

2.  Familial breast-ovarian cancer locus on chromosome 17q12-q23.

Authors:  S A Narod; J Feunteun; H T Lynch; P Watson; T Conway; J Lynch; G M Lenoir
Journal:  Lancet       Date:  1991-07-13       Impact factor: 79.321

3.  Etiologic factors of breast cancer elucidated by a study of unselected twins.

Authors:  N V Holm; M Hauge; B Harvald
Journal:  J Natl Cancer Inst       Date:  1980-08       Impact factor: 13.506

4.  Linkage of early-onset familial breast cancer to chromosome 17q21.

Authors:  J M Hall; M K Lee; B Newman; J E Morrow; L A Anderson; B Huey; M C King
Journal:  Science       Date:  1990-12-21       Impact factor: 47.728

5.  A breast-ovarian cancer susceptibility gene maps to chromosome 17q21.

Authors:  J Feunteun; S A Narod; H T Lynch; P Watson; T Conway; J Lynch; J Parboosingh; P O'Connell; R White; G M Lenoir
Journal:  Am J Hum Genet       Date:  1993-04       Impact factor: 11.025

6.  Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

Authors:  D F Easton; D T Bishop; D Ford; G P Crockford
Journal:  Am J Hum Genet       Date:  1993-04       Impact factor: 11.025

7.  DNA screening for breast/ovarian cancer susceptibility based on linked markers. A family study.

Authors:  H T Lynch; P Watson; T A Conway; J F Lynch; S M Slominski-Caster; S A Narod; J Feunteun; G Lenoir
Journal:  Arch Intern Med       Date:  1993-09-13

8.  The search for BRCA1.

Authors:  L S Friedman; E A Ostermeyer; E D Lynch; C I Szabo; L A Anderson; P Dowd; M K Lee; S E Rowell; J Boyd; M C King
Journal:  Cancer Res       Date:  1994-12-15       Impact factor: 12.701
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.