Literature DB >> 85691

Association of hepatitis B e-antigen (HBeAg) determinants with the core of Dane particles.

A R Neurath, N Strick.   

Abstract

Immunoprecipitates obtained by reacting Dane particle cores with human antibodies to hepatitis B core antigen (HBcAg) were chromatographed on columns of Sepharose 4B CL using 3 M-NaSCN as eluant. An antigen having the size and immunological specificity of monomeric e-antigen (HBeAg) was separated from HBcAg by this method. Antisera from animals immunized with HBcAg or HBeAg reacted not only with the antigen used for immunization but also with HBeAg and HBcAg, respectively. This indicates that HBeAg determinants are associated with the core of Dane particles.

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Year:  1979        PMID: 85691     DOI: 10.1099/0022-1317-42-3-645

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  4 in total

1.  Expression of cloned hepatitis B virus DNA in human cell cultures.

Authors:  S Z Hirschman; P Price; E Garfinkel; J Christman; G Acs
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

2.  Modulation of hepatitis B infection by intravenous application of an immunoglobulin preparation that contains antibodies to hepatitis B e and core antigens but not to hepatitis B surface antigen.

Authors:  W Stephan; A M Prince; B Brotman
Journal:  J Virol       Date:  1984-08       Impact factor: 5.103

3.  Core particles of hepatitis B virus and ground squirrel hepatitis virus. I. Relationship between hepatitis B core antigen- and ground squirrel hepatitis core antigen-associated polypeptides by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and tryptic peptide mapping.

Authors:  M A Feitelson; P L Marion; W S Robinson
Journal:  J Virol       Date:  1982-08       Impact factor: 5.103

4.  Core particles of hepatitis B virus and ground squirrel hepatitis virus. II. Characterization of the protein kinase reaction associated with ground squirrel hepatitis virus and hepatitis B virus.

Authors:  M A Feitelson; P L Marion; W S Robinson
Journal:  J Virol       Date:  1982-08       Impact factor: 5.103

  4 in total

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