BACKGROUND AND STUDY AIMS: The principle of endoscopic ultrasonography--introducing the transducer of an external imaging method, such as ultrasonography, in combination with an endoscope into the gastrointestinal tract for higher-resolution imaging--has also been applied to magnetic resonance imaging (MRI). We report here on our preliminary experience with a new method of endoscopic MRI in the upper gastrointestinal tract. PATIENTS AND METHODS: Endoscopic MRI was performed in 32 patients with esophageal (n = 8) or gastric diseases (n = 24), mostly tumors (n = 26). Most cancers were at an advanced stage (T3/T4). A prototype MRI endoscope connected to a 1.5 tesla MRI scanner was used. The accuracy of endoscopic MRI in visualizing and staging gastrointestinal lesions was assessed. RESULTS: The normal gastrointestinal wall consisted of three layers, and tumors were visualized as having a low signal intensity on both T1- and T2-weighted sequences. Destruction of the wall layers was found to be characteristic of malignancy. Sufficient images were obtained in seven of eight esophageal cases (88%), but in only 14 of 24 gastric cases (58%). In patients in whom adequate visualization was achieved, the endoscopic MRI results of local and regional staging were consistent with surgical, histopathological, CT and/or EUS results in all six esophageal cancer cases and in 89% (T stage) and 56% (N stage) of the nine patients with gastric cancer. CONCLUSIONS: These preliminary results of endoscopic MRI are the first to be reported in the English literature. They show the potential of the method for local and regional staging, three-dimensional visualization of lesions being a potential advantage. Further technical improvements are expected.
BACKGROUND AND STUDY AIMS: The principle of endoscopic ultrasonography--introducing the transducer of an external imaging method, such as ultrasonography, in combination with an endoscope into the gastrointestinal tract for higher-resolution imaging--has also been applied to magnetic resonance imaging (MRI). We report here on our preliminary experience with a new method of endoscopic MRI in the upper gastrointestinal tract. PATIENTS AND METHODS: Endoscopic MRI was performed in 32 patients with esophageal (n = 8) or gastric diseases (n = 24), mostly tumors (n = 26). Most cancers were at an advanced stage (T3/T4). A prototype MRI endoscope connected to a 1.5 tesla MRI scanner was used. The accuracy of endoscopic MRI in visualizing and staging gastrointestinal lesions was assessed. RESULTS: The normal gastrointestinal wall consisted of three layers, and tumors were visualized as having a low signal intensity on both T1- and T2-weighted sequences. Destruction of the wall layers was found to be characteristic of malignancy. Sufficient images were obtained in seven of eight esophageal cases (88%), but in only 14 of 24 gastric cases (58%). In patients in whom adequate visualization was achieved, the endoscopic MRI results of local and regional staging were consistent with surgical, histopathological, CT and/or EUS results in all six esophageal cancer cases and in 89% (T stage) and 56% (N stage) of the nine patients with gastric cancer. CONCLUSIONS: These preliminary results of endoscopic MRI are the first to be reported in the English literature. They show the potential of the method for local and regional staging, three-dimensional visualization of lesions being a potential advantage. Further technical improvements are expected.
Authors: Narong Khuntikeo; Attapol Titapun; Nittaya Chamadol; Wuttisak Boonphongsathien; Prakasit Sa-Ngiamwibool; Simon D Taylor-Robinson; Christopher A Wadsworth; Shuo Zhang; Evdokia M Kardoulaki; Richard R A Syms Journal: Hepat Med Date: 2020-07-27
Authors: Tobias Heye; Christian Kuntz; Marcus Düx; Jens Encke; Moritz Palmowski; Frank Autschbach; Frank Volke; Guenter Werner Kauffmann; Lars Grenacher Journal: Eur Radiol Date: 2006-05-30 Impact factor: 5.315
Authors: Narong Khuntikeo; Attapol Titapun; Nittaya Chamadol; Wuttisak Boonphongsathien; Prakasit Sa-Ngiamwibool; Simon D Taylor-Robinson; Christopher A Wadsworth; Shuo Zhang; Evdokia M Kardoulaki; Ian R Young; Richard R A Syms Journal: Hepat Med Date: 2020-03-24