Literature DB >> 8560774

A conserved sequence motif at the 5' terminus of the Southampton virus genome is characteristic of the Caliciviridae.

P R Lambden1, B Liu, I N Clarke.   

Abstract

We have determined the 5'terminal cDNA sequence for the genome of Southampton virus, a recently characterized, human, small round-structured virus (SRSV). Genomic RNA was extracted directly from a stool sample and amplified by RT-PCR by homopolymer tailing of the 3' terminus of the cDNA. The additional sequence increases the overall length of the Southampton virus genome by 12 nucleotides, resulting in a significant change to the genome organization by extending the first large open reading frame (ORF) by 51 amino acids. The 5'terminal bases pGpT and the presence of conserved genome and putative subgenomic RNA terminal motifs are now prominent features shared between the human SRSV Southampton virus and the animal caliciviruses rabbit hemorrhagic disease virus and feline calicivirus.

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Year:  1995        PMID： 8560774     DOI： 10.1007/bf01702595

Source DB:  PubMed          Journal:  Virus Genes        ISSN： 0920-8569            Impact factor:   2.332


  14 in total

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Authors:  M B Dinulos; D O Matson
Journal:  Pediatr Infect Dis J       Date:  1994-11       Impact factor: 2.129

6.  A simple and very efficient method for generating cDNA libraries.

Authors:  U Gubler; B J Hoffman
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

7.  Rabbit hemorrhagic disease virus--molecular cloning and nucleotide sequencing of a calicivirus genome.

Authors:  G Meyers; C Wirblich; H J Thiel
Journal:  Virology       Date:  1991-10       Impact factor: 3.616

8.  Identification of a human group C rotavirus in Malaysia.

Authors:  N B Rasool; M Hamzah; M Jegathesan; Y H Wong; Y Qian; K Y Green
Journal:  J Med Virol       Date:  1994-07       Impact factor: 2.327

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Authors:  J N Burroughs; F Brown
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10.  Genomic and subgenomic RNAs of rabbit hemorrhagic disease virus are both protein-linked and packaged into particles.

Authors:  G Meyers; C Wirblich; H J Thiel
Journal:  Virology       Date:  1991-10       Impact factor: 3.616
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  15 in total

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Journal:  Virus Genes       Date:  2000       Impact factor: 2.332

2.  Crystallization and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael acceptor inhibitor.

Authors:  R J Hussey; L Coates; R S Gill; J N Wright; M Sarwar; S Coker; P T Erskine; J B Cooper; S Wood; I N Clarke; P R Lambden; R Broadbridge; P M Shoolingin-Jordan
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Authors:  B Liu; I N Clarke; E O Caul; P R Lambden
Journal:  Virus Genes       Date:  1997       Impact factor: 2.332

Review 5.  Viral gastroenteritis: small round structured viruses, caliciviruses and astroviruses. Part I. The clinical and diagnostic perspective.

Authors:  E O Caul
Journal:  J Clin Pathol       Date:  1996-11       Impact factor: 3.411

6.  Methods for ascertaining norovirus disease burdens.

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Journal:  Hum Vaccin Immunother       Date:  2017-11-02       Impact factor: 3.452

7.  The genome of hawaii virus and its relationship with other members of the caliciviridae.

Authors:  M A Pletneva; S V Sosnovtsev; K Y Green
Journal:  Virus Genes       Date:  2001       Impact factor: 2.332

8.  Completion of the Norwalk virus genome sequence.

Authors:  M E Hardy; M K Estes
Journal:  Virus Genes       Date:  1996       Impact factor: 2.332

9.  Characterization of an enteropathogenic bovine calicivirus representing a potentially new calicivirus genus.

Authors:  J R Smiley; K O Chang; J Hayes; J Vinjé; L J Saif
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10.  Polyprotein processing in Southampton virus: identification of 3C-like protease cleavage sites by in vitro mutagenesis.

Authors:  B Liu; I N Clarke; P R Lambden
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103
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