Literature DB >> 8540503

Self-expanding metal stents for palliation of inoperable carcinoma of the esophagus and gastroesophageal junction.

G D De Palma1, G Galloro, L Sivero, E Di Matteo, O Labianca, S Siciliano, P Abbruzzese, C Catanzano.   

Abstract

OBJECTIVES: Rapid palliation of malignant dysphagia is usually possible with endoscopic implantation of plastic prosthesis, but this device has a high rate of complications. Recently expandable metal stents have become available that may have a reduced complications rate.
METHODS: This report details our experience with 32 patients treated from September of 1992 through June of 1994. Twenty-three patients were treated primarily with the Ultraflex esophageal prosthesis, and five patients were treated with postoperative malignant stricture, three with failed laser therapy and one with postradiation therapy malignant stricturing. Implantation was successful in 30/32 patients (94%). No major bleeding or perforation followed placement. The dysphagia score improved dramatically from 3 to 0.5. Twenty-six patients had a follow-up of at least 30 days. No stent migration occurred. Food impaction was seen in three patients, tumor ingrowth in three, and overgrowth in one patient. The median survival was 6.2 months with a range of 1.8-11.3 months.
CONCLUSIONS: Expandable metal stents are effective and safe for palliation of malignant obstruction of the esophagus and gastro-esophageal junction. However, long term problems remain to be addressed, such as ingrowth by tumor, food impaction, and limitation of stent expansion by tumor rigidity.

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Year:  1995        PMID: 8540503

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  3 in total

1.  Improving palliative treatment of patients with non-operable cancer of the oesophagus: training doctors and nurses in the use of self-expanding metal stents (SEMS) in Malawi.

Authors:  A Thumbs; L Vigna; J Bates; L Fullerton; A L Kushner
Journal:  Malawi Med J       Date:  2012-03       Impact factor: 0.875

2.  Safe oesophageal stent deployment using a checklist system instead of fluoroscopy.

Authors:  Muhammad S Khanzada; Abdelmonim E A Salih; Michael R Boland; Thomas N Walsh
Journal:  Surg Endosc       Date:  2022-05-09       Impact factor: 4.584

3.  Airway and esophageal stenting in patients with advanced esophageal cancer and pulmonary involvement.

Authors:  Fabrice Paganin; Laurent Schouler; Laurent Cuissard; Jean Baptiste Noel; Jean-Philippe Becquart; Mathieu Besnard; Laurent Verdier; Denis Rousseau; Claude Arvin-Berod; Arnaud Bourdin
Journal:  PLoS One       Date:  2008-08-29       Impact factor: 3.240

  3 in total

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