Literature DB >> 8536182

Genetic and environmental influences on growth.

R J Rona1, S Chinn.   

Abstract

OBJECTIVES: To provide an overview of the factors associated with growth in primary school children in England and Scotland and to provide information about the secular trend of growth in the last 20 years.
SETTING: Representative English and Scottish samples and an English inner city sample.
METHODS: The study had a mixed longitudinal design from 1972 to 1994. Between 8000 and 10,000 children participated in each survey. Height was measured in at least 95% of the children in most surveys, and 75% to 85% of parents provided information about family background. Main results are based on published information. Multiple regression was used for most of the analyses.
RESULTS: Parents' height, child's birth weight, mother's age at child's delivery, ethnic background and, in white children, family size are the only factors markedly associated with height. Variables that have traditionally been used to assess the possible effect of social conditions were generally not associated with height. The height increase was more marked in Scotland than England over the period 1972 to 1990, and the differences in height of children in the two countries is now minimal.
CONCLUSIONS: Most factors cannot be neatly classified as purely genetic or environmental, but seem to indicate that genes are relatively more important. Social factors usually assessed in growth studies do not have an important effect on growth. The marked increase of height over time indicates that the environment and social conditions have allowed children to grow taller. Sibship size is the only factor that was shown to be related to the secular trend in growth.

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Year:  1995        PMID: 8536182     DOI: 10.1177/096914139500200307

Source DB:  PubMed          Journal:  J Med Screen        ISSN: 0969-1413            Impact factor:   2.136


  5 in total

1.  Relation between number of siblings and adult mortality and stroke risk: 25 year follow up of men in the Collaborative study.

Authors:  C L Hart; G Davey Smith
Journal:  J Epidemiol Community Health       Date:  2003-05       Impact factor: 3.710

2.  The natural history of alpha angle in the last seventeen centuries.

Authors:  Roberto Seijas; Albert Pérez; David Barastegui; Emili Revilla; Carlos López de Celis; Jordi Català
Journal:  Arch Orthop Trauma Surg       Date:  2021-11-26       Impact factor: 2.928

3.  Childhood leg length and adult mortality: follow up of the Carnegie (Boyd Orr) Survey of Diet and Health in Pre-war Britain.

Authors:  D J Gunnell; G Davey Smith; S Frankel; K Nanchahal; F E Braddon; J Pemberton; T J Peters
Journal:  J Epidemiol Community Health       Date:  1998-03       Impact factor: 3.710

4.  Social inequalities in height: persisting differences today depend upon height of the parents.

Authors:  Bruna Galobardes; Valerie A McCormack; Peter McCarron; Laura D Howe; John Lynch; Debbie A Lawlor; George Davey Smith
Journal:  PLoS One       Date:  2012-01-06       Impact factor: 3.240

5.  Adult height and risk of breast cancer: a possible effect of early nutrition.

Authors:  T I Nilsen; L J Vatten
Journal:  Br J Cancer       Date:  2001-09-28       Impact factor: 7.640

  5 in total

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