| Literature DB >> 8533152 |
Abstract
Nucleotide excision repair (NER) uses the products of about 30 genes to remove a damage-containing oligonucleotide from cellular DNA. The transcription factor TFIIH is an essential component of NER. In man, defects in NER can result in three distinct genetic disorders, whose features can be ascribed to abnormalities in DNA repair or transcription.Entities:
Mesh:
Substances:
Year: 1995 PMID: 8533152 DOI: 10.1016/s0968-0004(00)89088-x
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807