| Literature DB >> 8526974 |
W G Honer1, G N Smith, J S Lapointe, G W MacEwan, L Kopala, S Altman.
Abstract
Regional measures of cortical sulcal and ventricular enlargement on computed tomography scan were studied in a clinical sample of patients treated with clozapine. Cortical sulci were significantly enlarged in clozapine nonresponders compared to responders. The Clinical Global Impressions score at discharge was related to the size of the posterior frontal and lateral temporal sulci, with large sulci predicting a poorer response to clozapine treatment.Entities:
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Year: 1995 PMID: 8526974 DOI: 10.1016/0893-133X(95)00017-8
Source DB: PubMed Journal: Neuropsychopharmacology ISSN: 0893-133X Impact factor: 7.853