Literature DB >> 8517170

Serotonin and amino acid content in platelets of autistic children.

L H Rolf1, F Y Haarmann, K H Grotemeyer, H Kehrer.   

Abstract

The platelet levels of serotonin and the amino acids aspartic acid, glutamine, glutamic acid and gamma-aminobutyric acid were measured in 18 drug-free autistic (DSM-III criteria) and 14 age-matched healthy children. Serotonin was significantly increased while the amino acids aspartic acid, glutamine, glutamic acid and gamma-aminobutyric acid were significantly decreased in comparison with the controls. It is suggested that the decline of the amino acids in platelets from autistic children represents a biochemical marker related to infantile autism.

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Year:  1993        PMID: 8517170     DOI: 10.1111/j.1600-0447.1993.tb03378.x

Source DB:  PubMed          Journal:  Acta Psychiatr Scand        ISSN: 0001-690X            Impact factor:   6.392


  34 in total

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Review 7.  The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment.

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