Literature DB >> 8516968

Myeloma--results of treatment 1986-1990.

P Kettle1, L Ranaghan, G M Markey, J H Robertson, Z R Desai, C Bharucha, T C Morris.   

Abstract

Sixty-nine patients with multiple myeloma diagnosed during a five year period at the Belfast City Hospital were followed until death or for a minimum of one year in a retrospective study of survival. Although the patients were unselected, survival data was found to be similar to results from trials in which patient selection had occurred. Overall median survival was thirty-two months. Median survival fell with advancing disease and was 47, 27 and 18 months for Durie-Salmon stages I, II and III respectively. Those patients presenting with a platelet count of < 100 x 10(9)/1 had a median survival of eight months in contrast to those with a platelet count > 100 x 10(9)/1 whose median survival was 36 months. Patients presenting in renal failure had a shorter median survival of 28 months compared to 46 months for those with normal renal function.

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Year:  1993        PMID: 8516968      PMCID: PMC2449015     

Source DB:  PubMed          Journal:  Ulster Med J        ISSN: 0041-6193


  19 in total

1.  Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy.

Authors:  W P Sheridan; C G Begley; C A Juttner; J Szer; L B To; D Maher; K M McGrath; G Morstyn; R M Fox
Journal:  Lancet       Date:  1992-03-14       Impact factor: 79.321

2.  Organized clinical investigation of cancer. X.

Authors:  H B LATOURETTE; I LAMPE; F J HODGES
Journal:  Med Bull (Ann Arbor)       Date:  1956-05

3.  Perspectives in multiple myeloma: survival, prognostic factors and disease complications in a single centre between 1975 and 1988.

Authors:  H C Rayner; A P Haynes; J R Thompson; N Russell; J Fletcher
Journal:  Q J Med       Date:  1991-06

4.  Prognostic factors and staging systems for multiple myeloma: comparisons between the Medical Research Council studies in the United Kingdom and the Southwest Oncology Group studies in the United States.

Authors:  K A Kelly; B Durie; I C Maclennan
Journal:  Hematol Oncol       Date:  1988 Apr-Jun       Impact factor: 5.271

5.  High-dose glucocorticoid treatment of resistant myeloma.

Authors:  R Alexanian; B Barlogie; D Dixon
Journal:  Ann Intern Med       Date:  1986-07       Impact factor: 25.391

6.  Prognostic value of pretreatment serum beta 2 microglobulin in myeloma: a Southwest Oncology Group Study.

Authors:  B G Durie; D Stock-Novack; S E Salmon; P Finley; J Beckord; J Crowley; C A Coltman
Journal:  Blood       Date:  1990-02-15       Impact factor: 22.113

7.  Autologous bone marrow transplantation in multiple myeloma: identification of prognostic factors.

Authors:  S Jagannath; B Barlogie; K Dicke; R Alexanian; G Zagars; B Cheson; F C Lemaistre; L Smallwood; K Pruitt; D O Dixon
Journal:  Blood       Date:  1990-11-01       Impact factor: 22.113

8.  Combined chemotherapy with ABCM versus melphalan for treatment of myelomatosis. The Medical Research Council Working Party for Leukaemia in Adults.

Authors:  I C MacLennan; C Chapman; J Dunn; K Kelly
Journal:  Lancet       Date:  1992-01-25       Impact factor: 79.321

9.  Allogeneic bone marrow transplantation in multiple myeloma. European Group for Bone Marrow Transplantation.

Authors:  G Gahrton; S Tura; P Ljungman; C Belanger; L Brandt; M Cavo; T Facon; A Granena; M Gore; A Gratwohl
Journal:  N Engl J Med       Date:  1991-10-31       Impact factor: 91.245

10.  Prognostic factors and classification in multiple myeloma.

Authors:  J F San Miguel; J Sànchez; M Gonzalez
Journal:  Br J Cancer       Date:  1989-01       Impact factor: 7.640

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