Literature DB >> 8504612

The effects of antibiotic-impregnated autogeneic cancellous bone graft on bone healing.

R W Lindsey1, R Probe, T Miclau, J W Alexander, S M Perren.   

Abstract

Autogeneic cancellous bone graft has been recommended as a vehicle for local antibiotic delivery. Its effect on graft incorporation, however, is unknown. The healing of defects grafted with tobramycin-impregnated cancellous bone were compared with those grafted with cancellous bone alone. Plane roentgenographs, microradiographs, bone density analyses, histologic examination, and biomechanical testing were performed on specimens throughout the course of healing. The presence of large concentrations of local tobramycin does not appear to affect the normal healing characteristics of cancellous bone graft.

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Year:  1993        PMID： 8504612

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN： 0009-921X            Impact factor:   4.176


  13 in total

1.  Comparison of various surgical methods in the treatment of implant-related infection.

Authors:  Muhittin Sener; Cemal Kazimoglu; Hasan Karapinar; Izge Günal; Ilhan Afşar; Asli Gamze Karataş Sener
Journal:  Int Orthop       Date:  2009-03-19       Impact factor: 3.075

2.  Polymer-controlled release of tobramycin from bone graft void filler.

Authors:  Amanda E Brooks; Benjamin D Brooks; Sherry N Davidoff; Paul C Hogrebe; Mark A Fisher; David W Grainger
Journal:  Drug Deliv Transl Res       Date:  2013-12       Impact factor: 4.617

Review 3.  [Potential of allogeneic bone grafts as antibiotic carriers : Effect of different preparation processes on efficacy].

Authors:  D C Coraça-Huber; M Nogler; K-D Kühn
Journal:  Orthopade       Date:  2018-01       Impact factor: 1.087

4.  Infected nonunions of long bones of the upper extremity: staged reconstruction using polymethylmethacrylate and bone graft impregnated with antibiotics.

Authors:  Christian Allende; Martin Mangupli; Julio Bagliardelli; Paula Diaz; Bartolome T Allende
Journal:  Chir Organi Mov       Date:  2009-10-30

5.  Local Injection of Aminoglycosides for Prophylaxis Against Infection in Open Fractures.

Authors:  Cheryl Reese Lawing; Feng-Chang Lin; Laurence E Dahners
Journal:  J Bone Joint Surg Am       Date:  2015-11-18       Impact factor: 5.284

6.  Antibiotic-impregnated bone grafts in orthopaedic and trauma surgery: a systematic review of the literature.

Authors:  Konstantinos Anagnostakos; Katrin Schröder
Journal:  Int J Biomater       Date:  2012-07-26

7.  Decal bone matrix as a local antibiotic delivery vehicle in a MRSA-infected bone model: An experimental study.

Authors:  Shyam K Saraf; Awadhesh Yadav; Santosh Nagwani; Mr Sen
Journal:  Indian J Orthop       Date:  2010-07       Impact factor: 1.251

8.  Lyophilized allogeneic bone tissue as an antibiotic carrier.

Authors:  Débora C Coraça-Huber; Christoph G Ammann; Michael Nogler; Manfred Fille; Lars Frommelt; Klaus-Dieter Kühn; Christian Fölsch
Journal:  Cell Tissue Bank       Date:  2016-09-08       Impact factor: 1.522

9.  Tissue engineering rib with the incorporation of biodegradable polymer cage and BMSCs/decalcified bone: an experimental study in a canine model.

Authors:  Hua Tang; Bin Wu; Xiong Qin; Lu Zhang; Jim Kretlow; Zhifei Xu
Journal:  J Cardiothorac Surg       Date:  2013-05-20       Impact factor: 1.637

10.  Strategies for the analysis of osteitic bone defects at the diaphysis of long bones.

Authors:  A H Tiemann; H G K Schmidt; R Braunschweig; G O Hofmann
Journal:  Strategies Trauma Limb Reconstr       Date:  2009-03-14
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