Literature DB >> 19876707

Infected nonunions of long bones of the upper extremity: staged reconstruction using polymethylmethacrylate and bone graft impregnated with antibiotics.

Christian Allende1, Martin Mangupli, Julio Bagliardelli, Paula Diaz, Bartolome T Allende.   

Abstract

This case series evaluates 12 patients presenting posttraumatic infected nonunions affecting long bones of the upper extremity, treated with staged reconstruction using polymethylmethacrylate spacers with antibiotics in the first stage and bone graft impregnated with antibiotics in the definitive surgical procedure. Five nonunions affected the humerus, four the ulna and three the radius. All nonunions were atrophic. Patient's age averaged 35.9 years. The size of the bony defect averaged 2.8 cm. Time between original trauma and revision surgery averaged 9.6 months. Follow-up averaged 19 months. All nonunions healed after an average of 5 months. DASH score at last follow-up averaged 15 points. Although two surgical procedures are needed, one to cure infection and another to achieve bony union, this approach for posttraumatic infected nonunions of long bones of the upper extremities represents a valid treatment alternative.

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Year:  2009        PMID: 19876707     DOI: 10.1007/s12306-009-0046-y

Source DB:  PubMed          Journal:  Chir Organi Mov        ISSN: 0009-4749


  25 in total

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Review 2.  Chronic posttraumatic osteomyelitis and infected nonunion of the tibia: current management concepts.

Authors:  Michael J Patzakis; Charalampos G Zalavras
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3.  Infected nonunion of the long bones.

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Review 4.  Local antibiotic delivery vehicles in the treatment of musculoskeletal infection.

Authors:  Arlen D Hanssen
Journal:  Clin Orthop Relat Res       Date:  2005-08       Impact factor: 4.176

Review 5.  Infected nonunion of the long bones.

Authors:  Peter A A Struijs; Rudolf W Poolman; Mohit Bhandari
Journal:  J Orthop Trauma       Date:  2007-08       Impact factor: 2.512

6.  Recalcitrant distal humeral and proximal forearm nonunion: salvage using an extended pedicled radial forearm osseous flap.

Authors:  Hannan Mullett; Michael Hausman; Carlos Zaidemberg
Journal:  J Trauma       Date:  2008-04

7.  Antibiotic cement-coated nails for the treatment of infected nonunions and segmental bone defects.

Authors:  Raghuram Thonse; Janet D Conway
Journal:  J Bone Joint Surg Am       Date:  2008-11       Impact factor: 5.284

Review 8.  Antimicrobial treatment of chronic osteomyelitis.

Authors:  J T Mader; M E Shirtliff; S C Bergquist; J Calhoun
Journal:  Clin Orthop Relat Res       Date:  1999-03       Impact factor: 4.176

9.  Treatment of long bone osteomyelitis with a mechanically stable intramedullar antibiotic dispenser: nineteen consecutive cases with a minimum of 12 months follow-up.

Authors:  Carlos Federico Sancineto; Jorge Daniel Barla
Journal:  J Trauma       Date:  2008-12

Review 10.  Nonunion: general principles and experimental data.

Authors:  E Carlos Rodriguez-Merchan; Francisco Forriol
Journal:  Clin Orthop Relat Res       Date:  2004-02       Impact factor: 4.176

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  4 in total

1.  Revision with plates of humeral nonunions secondary to failed intramedullary nailing.

Authors:  Christian Allende; Agustín Paz; Gonzalo Altube; Hernán Boccolini; Alejandro Malvarez; Bartolomé Allende
Journal:  Int Orthop       Date:  2013-11-21       Impact factor: 3.075

Review 2.  Acrylic bone cement: current concept review.

Authors:  B Magnan; M Bondi; T Maluta; E Samaila; L Schirru; C Dall'Oca
Journal:  Musculoskelet Surg       Date:  2013-07-27

3.  Antibiotic-impregnated bone grafts in orthopaedic and trauma surgery: a systematic review of the literature.

Authors:  Konstantinos Anagnostakos; Katrin Schröder
Journal:  Int J Biomater       Date:  2012-07-26

Review 4.  Autologous bone graft in the treatment of post-traumatic bone defects: a systematic review and meta-analysis.

Authors:  Matheus Lemos Azi; Alessandro Aprato; Irene Santi; Mauricio Kfuri; Alessandro Masse; Alexander Joeris
Journal:  BMC Musculoskelet Disord       Date:  2016-11-09       Impact factor: 2.362

  4 in total

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