Literature DB >> 8504250

Regulation of the HNF-1 homeodomain proteins by DCoH.

L P Hansen1, G R Crabtree.   

Abstract

The pattern of expression of homeodomain proteins often exceeds their apparent domain of activity. Tissue-specific proteins that modulate the in vivo activity of homeodomain proteins have been proposed to account for this functional restriction. The first identified example of such an accessory protein is DCoH, which confers transcriptional activity to the hepatocyte nuclear factor 1 and provides a model of how other accessory factors might modulate the function of homeodomain proteins.

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Year:  1993        PMID： 8504250     DOI： 10.1016/0959-437x(93)90030-s

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  14 in total

1.  A liver enhancer in the fibrinogen gene cluster.

Authors:  Alexandre Fort; Richard J Fish; Catia Attanasio; Roland Dosch; Axel Visel; Marguerite Neerman-Arbez
Journal:  Blood       Date:  2010-10-04       Impact factor: 22.113

2.  Hyperphenylalaninemia with high levels of 7-biopterin is associated with mutations in the PCBD gene encoding the bifunctional protein pterin-4a-carbinolamine dehydratase and transcriptional coactivator (DCoH).

Authors:  B Thöny; F Neuheiser; L Kierat; M Blaskovics; P H Arn; P Ferreira; I Rebrin; J Ayling; N Blau
Journal:  Am J Hum Genet       Date:  1998-06       Impact factor: 11.025

Review 3.  Multiple steps in the regulation of transcription-factor level and activity.

Authors:  C F Calkhoven; G Ab
Journal:  Biochem J       Date:  1996-07-15       Impact factor: 3.857

4.  Regulation of the gene for human dipeptidyl peptidase IV by hepatocyte nuclear factor 1 alpha.

Authors:  R H Erickson; J R Gum; C D Lotterman; J W Hicks; R S Lai; Y S Kim
Journal:  Biochem J       Date:  1999-02-15       Impact factor: 3.857

5.  Identification of hepatic nuclear factor 1 binding sites in the 5' flanking region of the human phenylalanine hydroxylase gene: implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system.

Authors:  X D Lei; S Kaufman
Journal:  Proc Natl Acad Sci U S A       Date:  1998-02-17       Impact factor: 11.205

6.  Differential expression of chicken dimerization cofactor of hepatocyte nuclear factor-1 (DcoH) and its novel counterpart, DcoHalpha.

Authors:  H Kim; S You; L K Foster; J Farris; Y J Choi; D N Foster
Journal:  Biochem J       Date:  2001-03-15       Impact factor: 3.857

7.  High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue.

Authors:  J D Cronk; J A Endrizzi; T Alber
Journal:  Protein Sci       Date:  1996-10       Impact factor: 6.725

8.  A limited upstream region of the human sucrase-isomaltase gene confers glucose-regulated expression on a heterologous gene.

Authors:  A Rodolosse; I Chantret; M Lacasa; G Chevalier; A Zweibaum; D Swallow; M Rousset
Journal:  Biochem J       Date:  1996-04-01       Impact factor: 3.857

9.  Studies on the enzymatic and transcriptional activity of the dimerization cofactor for hepatocyte nuclear factor 1.

Authors:  G Johnen; S Kaufman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-09       Impact factor: 11.205

10.  Diabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface.

Authors:  Q X Hua; M Zhao; N Narayana; S H Nakagawa; W Jia; M A Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-29       Impact factor: 11.205
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