Literature DB >> 8504248

Regulation of the beta-globin locus.

M Crossley1, S H Orkin.   

Abstract

Transcription of the human beta-globin gene cluster depends upon upstream regulatory sequences, which are collectively termed the locus control region. Recent studies have provided new insights into how the individual genes of the cluster are regulated through development. The crux of transcriptional activation is how the locus control region communicates with the gene-proximal regulatory elements.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8504248     DOI： 10.1016/0959-437x(93)90028-n

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  32 in total

1.  Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells.

Authors:  M Crossley; E Whitelaw; A Perkins; G Williams; Y Fujiwara; S H Orkin
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

2.  Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.

Authors:  C Garner; J Mitchell; T Hatzis; J Reittie; M Farrall; S L Thein
Journal:  Am J Hum Genet       Date:  1998-06       Impact factor: 11.025

3.  Characterization of the chicken beta-globin insulator.

Authors:  J H Chung; A C Bell; G Felsenfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1997-01-21       Impact factor: 11.205

4.  BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene.

Authors:  Michael B Chase; Sidong Fu; Susanne B Haga; Gregory Davenport; Holly Stevenson; Khanh Do; Doris Morgan; Alex L Mah; Patricia E Berg
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

5.  A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes.

Authors:  E J Kelly; E P Sandgren; R L Brinster; R D Palmiter
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-16       Impact factor: 11.205

6.  A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene.

Authors:  Z Wang; S A Liebhaber
Journal:  EMBO J       Date:  1999-04-15       Impact factor: 11.598

7.  Imprinting-mutation mechanisms in Prader-Willi syndrome.

Authors:  T Ohta; T A Gray; P K Rogan; K Buiting; J M Gabriel; S Saitoh; B Muralidhar; B Bilienska; M Krajewska-Walasek; D J Driscoll; B Horsthemke; M G Butler; R D Nicholls
Journal:  Am J Hum Genet       Date:  1999-02       Impact factor: 11.025

8.  Epigenomics reveals a functional genome anatomy and a new approach to common disease.

Authors:  Andrew P Feinberg
Journal:  Nat Biotechnol       Date:  2010-10       Impact factor: 54.908

9.  Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells.

Authors:  Alister P W Funnell; Christopher A Maloney; Lucinda J Thompson; Janelle Keys; Michael Tallack; Andrew C Perkins; Merlin Crossley
Journal:  Mol Cell Biol       Date:  2007-02-05       Impact factor: 4.272

10.  An upstream control region required for inducible transcription of the mouse H1(zero) histone gene during terminal differentiation.

Authors:  Y Dong; D Liu; A I Skoultchi
Journal:  Mol Cell Biol       Date:  1995-04       Impact factor: 4.272
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.