A simple and reproducible method for analysis of chromatin condensation.

A method for examination of chromatin condensation with the help of gel electrophoresis in low-density agarose gels was suggested. This method provides a way for the degree of chromatin condensation to be estimated at different ionic conditions of the medium. It led to results which are in close agreement with the results of other traditional methods. Thus it was inferred that this method offers an alternative to the method of density-gradient ultracentrifugation for chromatin condensation study.