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Literature DB >> 8503661

Gene therapy for cystic fibrosis.

C Coutelle¹, N Caplen, S Hart, C Huxley, R Williamson.

Abstract

Entities: Disease

Mesh：

Substances：
Liposomes

Year: 1993 PMID： 8503661 PMCID： PMC1029257 DOI： 10.1136/adc.68.4.437

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

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29 in total

1. Identification of the cystic fibrosis gene: genetic analysis.

Authors: B Kerem; J M Rommens; J A Buchanan; D Markiewicz; T K Cox; A Chakravarti; M Buchwald; L C Tsui
Journal: Science Date: 1989-09-08 Impact factor: 47.728

2. Biopsy of human preimplantation embryos and sexing by DNA amplification.

Authors: A H Handyside; J K Pattinson; R J Penketh; J D Delhanty; R M Winston; E G Tuddenham
Journal: Lancet Date: 1989-02-18 Impact factor: 79.321

3. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

Authors: J R Riordan; J M Rommens; B Kerem; N Alon; R Rozmahel; Z Grzelczak; J Zielenski; S Lok; N Plavsic; J L Chou
Journal: Science Date: 1989-09-08 Impact factor: 47.728

4. Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo.

Authors: M A Rosenfeld; W Siegfried; K Yoshimura; K Yoneyama; M Fukayama; L E Stier; P K Pääkkö; P Gilardi; L D Stratford-Perricaudet; M Perricaudet
Journal: Science Date: 1991-04-19 Impact factor: 47.728

5. Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells.

Authors: D P Rich; M P Anderson; R J Gregory; S H Cheng; S Paul; D M Jefferson; J D McCann; K W Klinger; A E Smith; M J Welsh
Journal: Nature Date: 1990-09-27 Impact factor: 49.962

6. Expression and characterization of the cystic fibrosis transmembrane conductance regulator.

Authors: R J Gregory; S H Cheng; D P Rich; J Marshall; S Paul; K Hehir; L Ostedgaard; K W Klinger; M J Welsh; A E Smith
Journal: Nature Date: 1990-09-27 Impact factor: 49.962

7. Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer.

Authors: M L Drumm; H A Pope; W H Cliff; J M Rommens; S A Marvin; L C Tsui; F S Collins; R A Frizzell; J M Wilson
Journal: Cell Date: 1990-09-21 Impact factor: 41.582

8. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis.

Authors: L G Johnson; J C Olsen; B Sarkadi; K L Moore; R Swanstrom; R C Boucher
Journal: Nat Genet Date: 1992-09 Impact factor: 38.330

9. Identification of the cystic fibrosis gene: chromosome walking and jumping.

Authors: J M Rommens; M C Iannuzzi; B Kerem; M L Drumm; G Melmer; M Dean; R Rozmahel; J L Cole; D Kennedy; N Hidaka
Journal: Science Date: 1989-09-08 Impact factor: 47.728

10. Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.

Authors: R C Boucher; M J Stutts; M R Knowles; L Cantley; J T Gatzy
Journal: J Clin Invest Date: 1986-11 Impact factor: 14.808

6 in total

Gene therapy for cystic fibrosis.

1. Identification of the cystic fibrosis gene: genetic analysis.

2. Biopsy of human preimplantation embryos and sexing by DNA amplification.

3. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

4. Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo.

5. Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells.

6. Expression and characterization of the cystic fibrosis transmembrane conductance regulator.

7. Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer.

8. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis.

9. Identification of the cystic fibrosis gene: chromosome walking and jumping.

10. Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.

1. Costs, effects, and savings of screening for cystic fibrosis gene carriers.

2. Gene transfer mediated by alpha2-macroglobulin.

3. Gene therapy begins.

4. Paediatric lung transplantation: the agony and the ecstasy.

Review 5. New perspectives in understanding and management of the respiratory disease in cystic fibrosis.

Review 6. Response to treatment in hereditary metabolic disease: 1993 survey and 10-year comparison.