Literature DB >> 8503390

Fatal hyperphosphatemia following Fleet Phospo-Soda in a patient with colonic ileus.

R Fass1, S Do, L J Hixson.   

Abstract

A fatal case of hyperphosphatemia secondary to enteral administration of Fleet Phospo-Soda is presented. A 64-yr-old male admitted for theophylline toxicity was treated with activated charcoal and sorbitol, but subsequently developed colonic ileus. Two sequential doses of Phospo-Soda were administered to facilitate clearance of the charcoal; however, this resulted in marked hyperphosphatemia, hypocalcemia, acidemia, and other electrolyte abnormalities, followed by the patient's demise. This case is added to several other reports about the risks of injudicious use of sodium phosphate cathartics.

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Year:  1993        PMID: 8503390

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  16 in total

1.  Phosphate enema toxicosis in a pygmy goat wether.

Authors:  Shirani A Hickman; Marjorie S Gill; Steven L Marks; Julie A Smith; Gary A Sod
Journal:  Can Vet J       Date:  2004-10       Impact factor: 1.008

2.  A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES).

Authors:  Steven D Wexner; David E Beck; Todd H Baron; Robert D Fanelli; Neil Hyman; Bo Shen; Kevin E Wasco
Journal:  Surg Endosc       Date:  2006-06-08       Impact factor: 4.584

Review 3.  Oral colorectal cleansing preparations in adults.

Authors:  Sherief Shawki; Steven D Wexner
Journal:  Drugs       Date:  2008       Impact factor: 9.546

4.  Symptomatic hypocalcemia, hypomagnesemia, and hyperphosphatemia secondary to Fleet's Phospho-Soda colonoscopy preparation in a patient with a jejunoileal bypass.

Authors:  E D Ehrenpreis; J M Wieland; J Cabral; V Estevez; D Zaitman; K Secrest
Journal:  Dig Dis Sci       Date:  1997-04       Impact factor: 3.199

Review 5.  The safety of osmotically acting cathartics in colonic cleansing.

Authors:  Caroline Nyberg; Jakob Hendel; Ole H Nielsen
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-08-24       Impact factor: 46.802

6.  Effects of a 250-mL enema containing sodium phosphate on electrolyte concentrations in healthy volunteers: An open-label, randomized, controlled, two-period, crossover clinical trial.

Authors:  Belén Sédaba; Josh R Azanza; Miguel A Campanero; Emilio Garcia-Quetglas; Maria Josh Muñoz; Santiago Marco
Journal:  Curr Ther Res Clin Exp       Date:  2006-09

Review 7.  Mechanism of action and toxicities of purgatives used for colonoscopy preparation.

Authors:  Margaret Adamcewicz; Dilip Bearelly; Gail Porat; Frank K Friedenberg
Journal:  Expert Opin Drug Metab Toxicol       Date:  2011-01       Impact factor: 4.481

Review 8.  A review of drug-induced hypocalcemia.

Authors:  George Liamis; Haralampos J Milionis; Moses Elisaf
Journal:  J Bone Miner Metab       Date:  2009       Impact factor: 2.626

9.  A novel phosphorus repletion strategy in a patient with duodenal perforation.

Authors:  Thomas Kemmerly; Carolyn Vuong; Jonathan D Kaunitz
Journal:  Nutr Clin Pract       Date:  2014-04-17       Impact factor: 3.080

Review 10.  Adverse renal and metabolic effects associated with oral sodium phosphate bowel preparation.

Authors:  Eliot C Heher; Samuel O Thier; Helmut Rennke; Benjamin D Humphreys
Journal:  Clin J Am Soc Nephrol       Date:  2008-07-02       Impact factor: 8.237

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