Literature DB >> 24743045

A novel phosphorus repletion strategy in a patient with duodenal perforation.

Thomas Kemmerly1, Carolyn Vuong, Jonathan D Kaunitz.   

Abstract

We describe a case in which a patient receiving parenteral nutrition (PN) developed hypophosphatemia. Due to lack of availability of parenteral phosphate supplements, we chose to restore phosphate using diluted hypertonic sodium phosphate enemas. Due to the recent shortages of parenteral minerals and vitamins, such an alternate means of repletion is of increasing importance. Diluted hypertonic sodium phosphate enemas are inexpensive, easy to administer, and effective since phosphate is readily absorbed across the rectal mucosa. We hope that through this type of repletion, life-threatening hypophosphatemia among patients receiving PN can be avoided.

Entities:  

Keywords:  GI access; adult; drug shortage; duodenum; enema; enteral access; fluids-electrolytes/acid-base; life cycle; minerals/trace elements; nutrition; parenteral formulas/compounding; parenteral nutrition; phosphates; phosphorus

Mesh:

Substances:

Year:  2014        PMID: 24743045      PMCID: PMC4844180          DOI: 10.1177/0884533614529997

Source DB:  PubMed          Journal:  Nutr Clin Pract        ISSN: 0884-5336            Impact factor:   3.080


  17 in total

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Authors:  J J Y Tan; J J Tjandra
Journal:  Colorectal Dis       Date:  2006-05       Impact factor: 3.788

2.  Hypophosphatemia-associated respiratory muscle weakness in a general inpatient population.

Authors:  T R Gravelyn; N Brophy; C Siegert; M Peters-Golden
Journal:  Am J Med       Date:  1988-05       Impact factor: 4.965

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Journal:  N Engl J Med       Date:  1977-10-27       Impact factor: 91.245

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Journal:  Am J Gastroenterol       Date:  1993-06       Impact factor: 10.864

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Authors:  A G Agusti; A Torres; R Estopa; A Agustividal
Journal:  Crit Care Med       Date:  1984-02       Impact factor: 7.598

7.  A comparison of bowel preparations for flexible sigmoidoscopy: oral magnesium citrate combined with oral bisacodyl, one hypertonic phosphate enema, or two hypertonic phosphate enemas.

Authors:  R K Fincher; E M Osgard; J L Jackson; J S Strong; R K Wong
Journal:  Am J Gastroenterol       Date:  1999-08       Impact factor: 10.864

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Journal:  Acta Chir Scand       Date:  1988 Jul-Aug

Review 9.  Treatment of hypophosphatemia in the intensive care unit: a review.

Authors:  Daniël A Geerse; Alexander J Bindels; Michael A Kuiper; Arnout N Roos; Peter E Spronk; Marcus J Schultz
Journal:  Crit Care       Date:  2010-08-03       Impact factor: 9.097

10.  Effect of hypophosphatemia on diaphragmatic contractility in patients with acute respiratory failure.

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Journal:  N Engl J Med       Date:  1985-08-15       Impact factor: 91.245

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  2 in total

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2.  An Alternative Approach to Treatment of Hypophosphatemia in Nonsurgical Critically Ill Patients in Countries With Limited Resources.

Authors:  Tijana Kovačević; Peđja Kovačević; Boris Tomić; Saša Dragić; Danica Momčičević
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  2 in total

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