Literature DB >> 850310

RNase activity in human interferon preparations.

R A Winchurch, T P Karpetsky, C C Levy, K Cantell.   

Abstract

The level of RNase activity in human interferon preparations was examined. Although sequential purification of interferon resulted in nearly a 300-fold increase in specific activity, RNase-specific activity remained more or less constant. The implications of this finding for the analyses of the mode of action of interferon are discussed.

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Year:  1977        PMID： 850310      PMCID： PMC515671          DOI： 10.1128/JVI.21.3.1247-1248.1977

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  9 in total

1.  Blocks in elongation and initiation of protein synthesis induced by interferon treatment in mouse L cells.

Authors:  J Content; B Lebleu; U Nudel; A Zilberstein; H Berissi; M Revel
Journal:  Eur J Biochem       Date:  1975-05

2.  Interferon action II. Membrane-bound alkaline ribonuclease activity in chick embryo cells manifesting interferon-mediated interference.

Authors:  P I Marcus; T M Terry; S Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Correlation between the antiviral effect of interferon treatment and the inhibition of in vitro mRNA translation in noninfected L cells.

Authors:  E Falcoff; R Falcoff; B Lebleu; M Revel
Journal:  J Virol       Date:  1973-09       Impact factor: 5.103

4.  Inhibition of protein synthesis directed by added viral and cellular messenger RNAs in extracts of interferon-treated Ehrlich ascites tumor cells. Location and dominance of the inhibitor(s).

Authors:  S L Gupta; M L Sopori; P Lengyel
Journal:  Biochem Biophys Res Commun       Date:  1973-09-18       Impact factor: 3.575

5.  Circulating interferon in rabbits after administration of human interferon by different routes.

Authors:  K Cantell; L Pyhälä
Journal:  J Gen Virol       Date:  1973-07       Impact factor: 3.891

6.  Interferon treatment inhibits Mengo RNA and haemoglobin mRNA translation in cell-free extracts of L cells.

Authors:  E Falcoff; R Falcoff; B Lebleu; M Revel
Journal:  Nat New Biol       Date:  1972-11-29

Review 7.  Human leukocyte interferon: production, purification, stability, and animal experiments.

Authors:  K Cantell; S Hirvonen; K E Mogensen; L Pyhälä
Journal:  In Vitro Monogr       Date:  1974

8.  Mechanism of interferon action: inhibition of viral messenger ribonucleic acid translation in L-cell extracts.

Authors:  R M Friedman; D H Metz; R M Esteban; D R Tovell; L A Ball; I M Kerr
Journal:  J Virol       Date:  1972-12       Impact factor: 5.103

9.  Effect of interferon upon the primary and secondary transcription of vesicular stomatitis and influenza viruses.

Authors:  P Repik; A Flamand; D H Bishop
Journal:  J Virol       Date:  1974-11       Impact factor: 5.103
  9 in total

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