| Literature DB >> 8497073 |
M T Boyd1, G R Simpson, A J Cann, M A Johnson, R A Weiss.
Abstract
Specific point mutations which affect viral tropism have been identified in both the V3 loop and in the CD4-binding region of the human immunodeficiency virus type 1 surface glycoprotein gp120. Here we report that a single point mutation in the first variable region (V1) of human immunodeficiency virus type 1 strain JRCSF is responsible for a change in viral tropism.Entities:
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Year: 1993 PMID: 8497073 PMCID: PMC237718 DOI: 10.1128/JVI.67.6.3649-3652.1993
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103