Literature DB >> 849292

Re-evaluation of amino-oxyacetate as an inhibitor.

S B Smith, S Briggs, K C Triebwasser, R A Freedland.   

Abstract

Data are provided which indicate that pyruvate and/or acetaldehyde can reverse the inhibition of alanine aminotransferase and aspartate aminotransferase by amino-oxyacetate. It was shown that acetaldehyde could reverse the inhibition of gluconeogenesis from alanine and that pyruvate could reverse the inhibition of urea synthesis by amino-oxyacetate.

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Year:  1977        PMID： 849292      PMCID： PMC1164619          DOI： 10.1042/bj1620453

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  Mechanism of the irreversible inhibition of aspartate aminotransferase by the bacterial toxin L-2-amino-4-methoxy-trans-3-butenoic acid.

Authors:  R R Rando; N Relyea; L Cheng
Journal:  J Biol Chem       Date:  1976-06-10       Impact factor: 5.157

2.  A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.

Authors:  K BURTON
Journal:  Biochem J       Date:  1956-02       Impact factor: 3.857

Review 3.  The metabolic significance of anion transport in mitochondria.

Authors:  A J Meijer; K Van Dam
Journal:  Biochim Biophys Acta       Date:  1974-12-30

4.  Effects of aminooxyacetate on the metabolism of isolated liver cells.

Authors:  R Rognstad; D G Clark
Journal:  Arch Biochem Biophys       Date:  1974-04-02       Impact factor: 4.013

5.  The pathway of gluconeogenesis in the cortex of guinea-pig kidney. Use of aminooxyacetate as a transaminase inhibitor.

Authors:  I D Longshaw; N L Bowen; C I Pogson
Journal:  Eur J Biochem       Date:  1972-02-15

6.  Effect of ornithine and lactate on urea synthesis in isolated hepatocytes.

Authors:  S Briggs; R A Freedland
Journal:  Biochem J       Date:  1976-11-15       Impact factor: 3.857

7.  Acceleration of gluconeogenesis from lactate by lysine (Short Communication).

Authors:  N W Cornell; P Lund; R Hems; H A Krebs
Journal:  Biochem J       Date:  1973-06       Impact factor: 3.857

8.  Role of anion translocation across the mitochondrial membrane in the regulation of urea synthesis from ammonia by isolated rat hepatocytes.

Authors:  A J Meijer; J A Gimpel; G A Deleeuw; J M Tager; J R Williamson
Journal:  J Biol Chem       Date:  1975-10-10       Impact factor: 5.157

9.  High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

Authors:  M N Berry; D S Friend
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539
  9 in total
  15 in total

1.  Effects of inhibition of ornithine aminotransferase or of general aminotransferases on urea and citrulline synthesis and on the levels of acetylglutamate in isolated rat hepatocytes.

Authors:  F Aniento; A Garcia-España; M Portolés; E Alonso; J R Cabo
Journal:  Mol Cell Biochem       Date:  1988-02       Impact factor: 3.396

Review 2.  Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition.

Authors:  Karim Zuhra; Fiona Augsburger; Tomas Majtan; Csaba Szabo
Journal:  Biomolecules       Date:  2020-04-30

3.  Amino acid and energy requirements for rat hepatocytes in primary culture.

Authors:  P E Schwarze; A E Solheim; P O Seglen
Journal:  In Vitro       Date:  1982-01

4.  Re-activation by glutamate or aspartate of amino-oxyacetate-inhibited aspartate aminotransferase in vitro and in isolated hepatocytes.

Authors:  N W Cornell; K E Crow; R P Whitefoot
Journal:  Biochem J       Date:  1981-07-15       Impact factor: 3.857

5.  Evidence for the participation of aspartate aminotransferase in hepatic glucose synthesis in the suckling newborn rat.

Authors:  P Ferré; D H Williamson
Journal:  Biochem J       Date:  1978-10-15       Impact factor: 3.857

6.  The regulation of glucose and pyruvate formation from glutamine and citric-acid-cycle intermediates in the kidney cortex of rats, dogs, rabbits and guinea pigs.

Authors:  M Watford; P Vinay; G Lemieux; A Gougoux
Journal:  Biochem J       Date:  1980-06-15       Impact factor: 3.857

7.  Selective inhibition of alanine aminotransferase and aspartate aminotransferase in rat hepatocytes.

Authors:  N W Cornell; P F Zuurendonk; M J Kerich; C B Straight
Journal:  Biochem J       Date:  1984-06-15       Impact factor: 3.857

8.  Branched-chain amino acid metabolism and alanine formation in rat muscles in vitro. Mitochondrial-cytosolic interrelationships.

Authors:  K Snell; D A Duff
Journal:  Biochem J       Date:  1985-02-01       Impact factor: 3.857

9.  Effect of adrenergic agonists and antagonists on alanine amino transferase, fructose-1:6-bisphosphatase and glucose production in hepatocytes.

Authors:  N A Begum; A G Datta
Journal:  Mol Cell Biochem       Date:  1992-08-18       Impact factor: 3.396

10.  Specificity of the effects of leucine and its metabolites on protein degradation in skeletal muscle.

Authors:  W E Mitch; A S Clark
Journal:  Biochem J       Date:  1984-09-15       Impact factor: 3.857
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