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Literature DB >> 16742833

Acceleration of gluconeogenesis from lactate by lysine (Short Communication).

N W Cornell¹, P Lund, R Hems, H A Krebs.

Abstract

l-Lysine (2mm) causes an increase (mean 60%) in the rate of gluconeogenesis from lactate in isolated liver cells. The effect is of a catalytic nature. No other amino acid has the same effect, though ornithine is slightly active. The effect is additional to the stimulatory effects of oleate and of dibutyryl cyclic AMP.

Entities: Chemical

Year: 1973 PMID： 16742833 PMCID： PMC1177859 DOI： 10.1042/bj1340671

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

5 in total

Review 1. Rate control of the tricarboxylic acid cycle.

Authors: H A Krebs
Journal: Adv Enzyme Regul Date: 1970

2. Control of gluconeogenesis in liver. II. Effects of glucagon, catecholamines, and adenosine 3',5'-monophosphate on gluconeogenesis in the perfused rat liver.

Authors: J H Exton; C R Park
Journal: J Biol Chem Date: 1968-08-25 Impact factor: 5.157

3. Carbohydrate metabolism of the perfused rat liver.

Authors: B D Ross; R Hems; R A Freedland; H A Krebs
Journal: Biochem J Date: 1967-11 Impact factor: 3.857

4. Gluconeogenesis in the perfused rat liver.

Authors: R Hems; B D Ross; M N Berry; H A Krebs
Journal: Biochem J Date: 1966-11 Impact factor: 3.857

5. High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

Authors: M N Berry; D S Friend
Journal: J Cell Biol Date: 1969-12 Impact factor: 10.539

5 in total

36 in total

1. Gluconeogenesis stimulated by extracellular ATP is triggered by the initial increase in the intracellular Ca2+ concentration of the periphery of hepatocytes.

Authors: M Koike; T Kashiwagura; N Takeguchi
Journal: Biochem J Date: 1992-04-01 Impact factor: 3.857

8. The effect of acute ethanol treatment on rates of oxygen uptake, ethanol oxidation and gluconeogenesis in isolated rat hepatocytes.

Authors: K M Stowell; K E Crow
Journal: Biochem J Date: 1985-09-15 Impact factor: 3.857

9. Lactate-stimulated ethanol oxidation in isolated rat hepatocytes.

Authors: K E Crow; N W Cornell; R L Veech
Journal: Biochem J Date: 1978-04-15 Impact factor: 3.857

10. The effects L-leucine on the synthesis of urea, glutamate and glutamine by isolated rat liver cells.

Authors: J M Mourão; J D McGivan; J B Chappell
Journal: Biochem J Date: 1975-02 Impact factor: 3.857

Acceleration of gluconeogenesis from lactate by lysine (Short Communication).

Review 1. Rate control of the tricarboxylic acid cycle.

2. Control of gluconeogenesis in liver. II. Effects of glucagon, catecholamines, and adenosine 3',5'-monophosphate on gluconeogenesis in the perfused rat liver.

3. Carbohydrate metabolism of the perfused rat liver.

4. Gluconeogenesis in the perfused rat liver.

5. High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

1. Gluconeogenesis stimulated by extracellular ATP is triggered by the initial increase in the intracellular Ca2+ concentration of the periphery of hepatocytes.

2. Hydroxypyruvate as a gluconeogenic substrate in rat hepatocytes.

3. Preparation and characterization of isolated parenchymal cells from guinea pig liver.

4. Calcium metabolism in rat hepatocytes.

5. Long-term maintenance of low concentrations of fructose for the study of hepatic glucose phosphorylation.

6. Loss of cell constituents from hepatocytes on centrifugation.

7. Selective inhibition of alanine aminotransferase and aspartate aminotransferase in rat hepatocytes.

8. The effect of acute ethanol treatment on rates of oxygen uptake, ethanol oxidation and gluconeogenesis in isolated rat hepatocytes.

9. Lactate-stimulated ethanol oxidation in isolated rat hepatocytes.

10. The effects L-leucine on the synthesis of urea, glutamate and glutamine by isolated rat liver cells.