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Literature DB >> 848935

Amphotericin B susceptibility testing of yeasts with a bactec radiometric system.

Abstract

The effect of amphotericin B on CO(2) production was studied using a Bactec 225. A radiometric procedure for yeast susceptibility testing that requires 3 h of incubation was developed. A total of 48 yeast isolates was tested in this system and the results were correlated to tube dilution studies. The drug concentration causing at least a 44% decrease in CO(2) production correlated to the tube dilution minimal inhibitory concentration in 85% of isolates tested and was within one tube dilution of the minimal inhibitory concentration in over 95% of yeasts tested.

Entities: Chemical Species

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Year: 1977 PMID： 848935 PMCID： PMC351968 DOI： 10.1128/AAC.11.2.277

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

3 in total

Amphotericin B susceptibility testing of yeasts with a bactec radiometric system.

1. Rapid radiometric method of testing susceptibility of mycobacteria and slow-growing fungi to antimicrobial agents.

2. Metabolic inhibition as an index of bacterial susceptibility to drugs.

3. Automatic radiometric measurement of antibiotic effect on bacterial growth.

1. Radiometric determination of the concentration of amphotericin B in body fluids.

2. Radiometric method for determining the susceptibility of yeasts to 5-fluorocytosine.

3. Susceptibility testing of filamentous fungi to amphotericin B by a rapid radiometric method.