Literature DB >> 8485573

Universal community carrier screening for cystic fibrosis?

R Williamson1.   

Abstract

Approximately 5% of the Caucasian North European and North American populations are carriers of the gene defect causing cystic fibrosis (CF). Since the CF gene was isolated in 1989 and the common mutations identified, there has been debate as to whether community-wide screening for CF carriers should be offered. Pilot studies and new discussions are leading to a consensus that screening is now possible and will not lead to undue anxiety, but there is still no agreement as to cost, or how it will be used by those screening positive.

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Year:  1993        PMID: 8485573     DOI: 10.1038/ng0393-195

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


  12 in total

1.  Should we genetically test everyone for haemochromatosis?

Authors:  K Allen; R Williamson
Journal:  J Med Ethics       Date:  1999-04       Impact factor: 2.903

2.  Carrier screening in preconception consultation in primary care.

Authors:  Sylvia A Metcalfe
Journal:  J Community Genet       Date:  2011-12-20

3.  Cystic fibrosis carrier population screening in the primary care setting.

Authors:  S Loader; P Caldwell; A Kozyra; J C Levenkron; C D Boehm; H H Kazazian; P T Rowley
Journal:  Am J Hum Genet       Date:  1996-07       Impact factor: 11.025

4.  The views of general practitioners on community carrier screening for cystic fibrosis.

Authors:  M Boulton; C Cummings; R Williamson
Journal:  Br J Gen Pract       Date:  1996-05       Impact factor: 5.386

5.  PCR-based screening for cystic fibrosis carrier mutations in an ethnically diverse pregnant population.

Authors:  W W Grody; C Dunkel-Schetter; Z H Tatsugawa; M A Fox; C Y Fang; R M Cantor; J M Novak; H N Bass; B F Crandall
Journal:  Am J Hum Genet       Date:  1997-04       Impact factor: 11.025

Review 6.  The measurement of patient attitudes regarding prenatal and preconception genetic carrier screening and translational behavioral medicine: an integrative review.

Authors:  Jennifer J Shiroff; Mathew J Gregoski
Journal:  Transl Behav Med       Date:  2017-06       Impact factor: 3.046

7.  Acceptability of carrier screening for cystic fibrosis during pregnancy in a German population.

Authors:  U Jung; U Urner; K Grade; C Coutelle
Journal:  Hum Genet       Date:  1994-07       Impact factor: 4.132

8.  Cystic fibrosis heterozygote screening in 5,161 pregnant women.

Authors:  D R Witt; C Schaefer; P Hallam; S Wi; B Blumberg; A Fishbach; J Holtzman; S Kornfeld; R Lee; L Nemzer; R Palmer
Journal:  Am J Hum Genet       Date:  1996-04       Impact factor: 11.025

9.  Screening for carriers of cystic fibrosis--a general practitioner's perspective.

Authors:  M Modell
Journal:  BMJ       Date:  1993-10-02

10.  Education and testing strategy for large-scale cystic fibrosis carrier screening.

Authors:  Z H Tatsugawa; M A Fox; C Y Fang; J M Novak; R M Cantor; H N Bass; C Dunkel-Schetter; B F Crandall; W W Grody
Journal:  J Genet Couns       Date:  1994-12       Impact factor: 2.537

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