Literature DB >> 8482620

Malignant spinal cord compression: a prospective evaluation.

S Turner1, B Marosszeky, I Timms, J Boyages.   

Abstract

PURPOSE: To determine the influence of treatment on ambulancy, pain control and functional outcome of patients with Malignant Spinal Cord Compression. METHODS AND MATERIALS: One hundred and thirty-seven patients with Malignant Spinal Cord Compression presenting or referred to the Department of Radiation Oncology, Westmead Hospital between August 1, 1989 and August 1, 1990 were studied prospectively. Patients were treated with palliative radiation therapy alone, surgery followed by radiotherapy or surgery alone. Two patients were not treated. Post-treatment outcome was assessed in terms of ambulatory status, improvement in pain and functional independence using the Functional Independence Measure.
RESULTS: Thirteen of 16 patients (81%) who were ambulant pre-treatment remained ambulant after treatment. Two of 16 patients (16.5%) who were non-ambulant pre-treatment became ambulant following treatment. Pain improved following treatment in 22 of 30 patients (73%). This benefit was seen equally for ambulant and non-ambulant patients. A high level of functional independence was maintained in patients who remained ambulant.
CONCLUSION: We conclude that prompt treatment of patients with Malignant Spinal Cord Compression while still able to walk is effective in maintaining ambulancy and functional independence, and that treatment improves pain in most patients.

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Year:  1993        PMID: 8482620     DOI: 10.1016/0360-3016(93)90185-x

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  9 in total

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Authors:  Daniel Lubelski; Joseph E Tanenbaum; Taylor E Purvis; Thomas T Bomberger; Courtney Rory Goodwin; Ilya Laufer; Daniel M Sciubba
Journal:  CNS Oncol       Date:  2017-07-18

2.  Morbidity and mortality in patients with cancer who become nonambulatory after spinal cord compression: a case series on end-of-life care.

Authors:  Jocelin Huang; Aminah Jatoi
Journal:  J Palliat Med       Date:  2009-03       Impact factor: 2.947

3.  Defunctioning stoma in high ASA grade, aged patients, with bowel occlusion due to advanced cancer: is it still worthwhile?

Authors:  Corrado R Asteria; Gabriella Nesi; Chiara Minari; Paolo Viganò
Journal:  Support Care Cancer       Date:  2009-12-13       Impact factor: 3.603

4.  Spinal cord compression secondary to bone metastases from hepatocellular carcinoma.

Authors:  Dinesh Chandra Doval; Komal Bhatia; Ashok Kumar Vaid; Keechelat Pavithran; Jai Bhagwan Sharma; Digant Hazarika; Amarnath Jena
Journal:  World J Gastroenterol       Date:  2006-08-28       Impact factor: 5.742

Review 5.  Clinical outcome of metastatic spinal cord compression treated with surgical excision ± radiation versus radiation therapy alone: a systematic review of literature.

Authors:  Jaehon M Kim; Elena Losina; Christopher M Bono; Andrew J Schoenfeld; Jamie E Collins; Jeffrey N Katz; Mitchel B Harris
Journal:  Spine (Phila Pa 1976)       Date:  2012-01-01       Impact factor: 3.468

6.  Prognostic factors in a series of 504 breast cancer patients with metastatic spinal cord compression.

Authors:  D Rades; S Douglas; T Veninga; L J A Stalpers; A Bajrovic; V Rudat; S E Schild
Journal:  Strahlenther Onkol       Date:  2012-02-23       Impact factor: 3.621

7.  A prospective study comparing radiographer- and clinician-based localization for patients with metastatic spinal cord compression (MSCC) to assess the feasibility of a radiographer-led service.

Authors:  Craig Lacey; Clare Ockwell; Imogen Locke; Karen Thomas; Julie Hendry; Helen McNair
Journal:  Br J Radiol       Date:  2015-08-18       Impact factor: 3.039

8.  Interstitial 125I seeds implantation to treat spinal metastatic and primary paraspinal malignancies.

Authors:  Junjie Wang; Huishu Yuan; Qingjun Ma; Xiaoguang Liu; Hao Wang; Yuliang Jiang; Suqing Tian; Ruijie Yang
Journal:  Med Oncol       Date:  2009-04-10       Impact factor: 3.064

9.  Metastatic epidural spinal cord compression: does timing of surgery influence the chance of neurological recovery? An observational case-control study.

Authors:  Valerio Pipola; Silvia Terzi; Giuseppe Tedesco; Stefano Bandiera; Giovanni Barbanti Bròdano; Riccardo Ghermandi; Gisberto Evangelisti; Marco Girolami; Alessandro Gasbarrini
Journal:  Support Care Cancer       Date:  2018-03-30       Impact factor: 3.603

  9 in total

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