Literature DB >> 8478340

Altered muropeptide composition in Staphylococcus aureus strains with an inactivated femA locus.

B L de Jonge1, T Sidow, Y S Chang, H Labischinski, B Berger-Bachi, D A Gage, A Tomasz.   

Abstract

Tn551 inactivation of femA, a factor involved in methicillin resistance of Staphylococcus aureus, caused the production of peptidoglycan in which the fraction of monoglycyl- and serine-containing muropeptides was increased at the expense of pentaglycyl muropeptides. femA mutants have a specific block in the biosynthesis of pentaglycine cross bridges after the addition of the first glycine residue.

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Year:  1993        PMID： 8478340      PMCID： PMC204585          DOI： 10.1128/jb.175.9.2779-2782.1993

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  16 in total

1.  Suppression of autolysis and cell wall turnover in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain.

Authors:  B L de Jonge; H de Lencastre; A Tomasz
Journal:  J Bacteriol       Date:  1991-02       Impact factor: 3.490

2.  Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A.

Authors:  B L de Jonge; Y S Chang; D Gage; A Tomasz
Journal:  J Biol Chem       Date:  1992-06-05       Impact factor: 5.157

3.  Conversion of a homogeneously methicillin-resistant strain of Staphylococcus aureus to heterogeneous resistance by Tn551-mediated insertional inactivation.

Authors:  J Kornblum; B J Hartman; R P Novick; A Tomasz
Journal:  Eur J Clin Microbiol       Date:  1986-12       Impact factor: 3.267

4.  Abnormal peptidoglycan produced in a methicillin-resistant strain of Staphylococcus aureus grown in the presence of methicillin: functional role for penicillin-binding protein 2A in cell wall synthesis.

Authors:  B L de Jonge; A Tomasz
Journal:  Antimicrob Agents Chemother       Date:  1993-02       Impact factor: 5.191

5.  Peptidoglycan cross-linking in Staphylococcus aureus. An apparent random polymerisation process.

Authors:  M A Snowden; H R Perkins
Journal:  Eur J Biochem       Date:  1990-07-31

6.  Insertional inactivation of the mec gene in a transposon mutant of a methicillin-resistant clinical isolate of Staphylococcus aureus.

Authors:  P Matthews; A Tomasz
Journal:  Antimicrob Agents Chemother       Date:  1990-09       Impact factor: 5.191

7.  femA, which encodes a factor essential for expression of methicillin resistance, affects glycine content of peptidoglycan in methicillin-resistant and methicillin-susceptible Staphylococcus aureus strains.

Authors:  H Maidhof; B Reinicke; P Blümel; B Berger-Bächi; H Labischinski
Journal:  J Bacteriol       Date:  1991-06       Impact factor: 3.490

8.  Involvement of multiple genetic determinants in high-level methicillin resistance in Staphylococcus aureus.

Authors:  K Murakami; A Tomasz
Journal:  J Bacteriol       Date:  1989-02       Impact factor: 3.490

9.  FemA, a host-mediated factor essential for methicillin resistance in Staphylococcus aureus: molecular cloning and characterization.

Authors:  B Berger-Bächi; L Barberis-Maino; A Strässle; F H Kayser
Journal:  Mol Gen Genet       Date:  1989-10

10.  Peptidoglycan composition in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain.

Authors:  B L de Jonge; Y S Chang; D Gage; A Tomasz
Journal:  J Biol Chem       Date:  1992-06-05       Impact factor: 5.157
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  34 in total

1.  Correlation between the structure of the bacterial peptidoglycan monomer unit, the specificity of transpeptidation, and susceptibility to beta-lactams.

Authors:  J van Heijenoort; L Gutmann
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-09       Impact factor: 11.205

2.  Identification of the UDP-MurNAc-pentapeptide:L-alanine ligase for synthesis of branched peptidoglycan precursors in Enterococcus faecalis.

Authors:  A Bouhss; N Josseaume; D Allanic; M Crouvoisier; L Gutmann; J L Mainardi; D Mengin-Lecreulx; J van Heijenoort; M Arthur
Journal:  J Bacteriol       Date:  2001-09       Impact factor: 3.490

Review 3.  FemABX peptidyl transferases: a link between branched-chain cell wall peptide formation and beta-lactam resistance in gram-positive cocci.

Authors:  S Rohrer; B Berger-Bächi
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

Review 4.  Consequences of the interaction of beta-lactam antibiotics with penicillin binding proteins from sensitive and resistant Staphylococcus aureus strains.

Authors:  H Labischinski
Journal:  Med Microbiol Immunol       Date:  1992       Impact factor: 3.402

5.  Antibiotic Resistance as a Stress Response: Recovery of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus "Auxiliary" (fem) Mutants by Induction of the Stringent Stress Response.

Authors:  Choon Keun Kim; Catarina Milheiriço; Hermínia de Lencastre; Alexander Tomasz
Journal:  Antimicrob Agents Chemother       Date:  2017-07-25       Impact factor: 5.191

6.  epr, which encodes glycylglycine endopeptidase resistance, is homologous to femAB and affects serine content of peptidoglycan cross bridges in Staphylococcus capitis and Staphylococcus aureus.

Authors:  M Sugai; T Fujiwara; K Ohta; H Komatsuzawa; M Ohara; H Suginaka
Journal:  J Bacteriol       Date:  1997-07       Impact factor: 3.490

Review 7.  Envelope Structures of Gram-Positive Bacteria.

Authors:  Mithila Rajagopal; Suzanne Walker
Journal:  Curr Top Microbiol Immunol       Date:  2017       Impact factor: 4.291

8.  The carboxyl terminus of peptidoglycan stem peptides is a determinant for methicillin resistance in Staphylococcus aureus.

Authors:  Boudewijn L M De Jonge; Douglas Gage; Naxing Xu
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

9.  Mechanisms of heteroresistance in methicillin-resistant Staphylococcus aureus.

Authors:  C Ryffel; A Strässle; F H Kayser; B Berger-Bächi
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

10.  Altered peptidoglycan composition in vancomycin-resistant Enterococcus faecalis.

Authors:  B L de Jonge; S Handwerger; D Gage
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191
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