Literature DB >> 8478113

Biochemical and immunological properties of two forms of pertactin, the 69,000-molecular-weight outer membrane protein of Bordetella pertussis.

J W Gotto1, T Eckhardt, P A Reilly, J V Scott, J L Cowell, T N Metcalf, K Mountzouros, J J Gibbons, M Siegel.   

Abstract

Two apparent isoforms of the virulence-associated 69,000-molecular-weight protein pertactin were purified from Bordetella pertussis. Mass spectrometry showed a difference of 2,060 Da, which may result from differential C-terminal cleavage of a larger precursor. Both forms were protective in a mouse model, eliciting bactericidal antibodies and reducing respiratory tract colonization.

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Year:  1993        PMID： 8478113      PMCID： PMC280825          DOI： 10.1128/iai.61.5.2211-2215.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  19 in total

1.  A simple chemically defined medium for the production of phase I Bordetella pertussis.

Authors:  D W Stainer; M J Scholte
Journal:  J Gen Microbiol       Date:  1970-10

2.  Identification of a 69-kilodalton nonfimbrial protein as an agglutinogen of Bordetella pertussis.

Authors:  M J Brennan; Z M Li; J L Cowell; M E Bisher; A C Steven; P Novotny; C R Manclark
Journal:  Infect Immun       Date:  1988-12       Impact factor: 3.441

3.  Construction and characterization in vivo of Bordetella pertussis aroA mutants.

Authors:  M Roberts; D Maskell; P Novotny; G Dougan
Journal:  Infect Immun       Date:  1990-03       Impact factor: 3.441

4.  A comprehensive set of sequence analysis programs for the VAX.

Authors:  J Devereux; P Haeberli; O Smithies
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

5.  Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis.

Authors:  I G Charles; G Dougan; D Pickard; S Chatfield; M Smith; P Novotny; P Morrissey; N F Fairweather
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Bordetella pertussis filamentous hemagglutinin: evaluation as a protective antigen and colonization factor in a mouse respiratory infection model.

Authors:  A Kimura; K T Mountzouros; D A Relman; S Falkow; J L Cowell
Journal:  Infect Immun       Date:  1990-01       Impact factor: 3.441

7.  Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells.

Authors:  E Leininger; M Roberts; J G Kenimer; I G Charles; N Fairweather; P Novotny; M J Brennan
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-15       Impact factor: 11.205

8.  Protective surface antigen P69 of Bordetella pertussis: its characterization and very high level expression in Escherichia coli.

Authors:  A J Makoff; M D Oxer; S P Ballantine; N F Fairweather; I G Charles
Journal:  Biotechnology (N Y)       Date:  1990-11

9.  Protective efficacy of the Takeda acellular pertussis vaccine combined with diphtheria and tetanus toxoids following household exposure of Japanese children.

Authors:  E A Mortimer; M Kimura; J D Cherry; H Kuno-Sakai; M G Stout; C L Dekker; R Hayashi; Y Miyamoto; J V Scott; T Aoyama
Journal:  Am J Dis Child       Date:  1990-08

10.  Characterization of the protective capacity and immunogenicity of the 69-kD outer membrane protein of Bordetella pertussis.

Authors:  R D Shahin; M J Brennan; Z M Li; B D Meade; C R Manclark
Journal:  J Exp Med       Date:  1990-01-01       Impact factor: 14.307
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  8 in total

1.  Acellular pertussis vaccines and complement killing of Bordetella pertussis.

Authors:  Alison A Weiss; Angela K Patton; Scott H Millen; Swei-Ju Chang; Joel I Ward; David I Bernstein
Journal:  Infect Immun       Date:  2004-12       Impact factor: 3.441

Review 2.  Type V protein secretion pathway: the autotransporter story.

Authors:  Ian R Henderson; Fernando Navarro-Garcia; Mickaël Desvaux; Rachel C Fernandez; Dlawer Ala'Aldeen
Journal:  Microbiol Mol Biol Rev       Date:  2004-12       Impact factor: 11.056

3.  Antibody responses to Bordetella bronchiseptica in vaccinated and infected dogs.

Authors:  John Ellis; Carrie Rhodes; Stacey Lacoste; Steven Krakowka
Journal:  Can Vet J       Date:  2014-09       Impact factor: 1.008

4.  Cloning and sequencing of a Bordetella pertussis serum resistance locus.

Authors:  R C Fernandez; A A Weiss
Journal:  Infect Immun       Date:  1994-11       Impact factor: 3.441

5.  Differential regulation of type III secretion and virulence genes in Bordetella pertussis and Bordetella bronchiseptica by a secreted anti-σ factor.

Authors:  Umesh Ahuja; Bhumika Shokeen; Ning Cheng; Yeonjoo Cho; Charles Blum; Giovanni Coppola; Jeff F Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-16       Impact factor: 11.205

6.  Characterization of human bactericidal antibodies to Bordetella pertussis.

Authors:  A A Weiss; P S Mobberley; R C Fernandez; C M Mink
Journal:  Infect Immun       Date:  1999-03       Impact factor: 3.441

7.  Humanised monoclonal antibodies neutralise pertussis toxin by receptor blockade and reduced retrograde trafficking.

Authors:  Edith Acquaye-Seedah; Yimin Huang; Jamie N Sutherland; Andrea M DiVenere; Jennifer A Maynard
Journal:  Cell Microbiol       Date:  2018-09-23       Impact factor: 3.715

8.  Immunological Distinctions between Acellular and Whole-Cell Pertussis Immunizations of Baboons Persist for at Least One Year after Acellular Vaccine Boosting.

Authors:  Leah E Cole; Jinrong Zhang; Kristl M Pacheco; Philippe Lhéritier; Natalie G Anosova; Julie Piolat; Lingyi Zheng; Nathalie Reveneau
Journal:  Vaccines (Basel)       Date:  2020-12-02
  8 in total

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