Literature DB >> 8472916

A monoclonal antibody to Shigella dysenteriae serotype 13 cross-reacting with Shiga toxin.

F Qadri1, T Azim, A Hossain, D Islam, G Mondol, S M Faruque, M J Albert.   

Abstract

A monoclonal antibody (mAb ICT6) was produced against the newly described Shigella dysenteriae serotype type 13. The mAb was of IgM isotype and recognized purified Shiga toxin in ELISA and immunoblot. It also recognized periplasmic extract S. dysenteriae type 13 in immunoblot as did an affinity-purified polyclonal rabbit antiserum and a previously described monoclonal antibody to the B subunit of Shiga toxin. The mAb ICT6 did not neutralize the cytotoxic effects or S. dysenteriae type 13, Shiga toxin or periplasmic extracts of S. dysenteriae type 1 for HeLa cells.

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Year:  1993        PMID: 8472916     DOI: 10.1111/j.1574-6968.1993.tb06055.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN: 0378-1097            Impact factor:   2.742


  3 in total

1.  Monoclonal antibodies to the enterotoxin of Bacteroides fragilis: production, characterization, and immunodiagnostic application.

Authors:  F Qadri; M G Mohi; A Chowdhury; K Alam; T Azim; C Sears; R B Sack; M J Albert
Journal:  Clin Diagn Lab Immunol       Date:  1996-09

2.  Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli.

Authors:  J A Girón; F Qadri; T Azim; K J Jarvis; J B Kaper; M J Albert
Journal:  Infect Immun       Date:  1995-12       Impact factor: 3.441

Review 3.  Monoclonal antibodies and toxins--a perspective on function and isotype.

Authors:  Siu-Kei Chow; Arturo Casadevall
Journal:  Toxins (Basel)       Date:  2012-06-11       Impact factor: 4.546

  3 in total

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