Literature DB >> 8464492

Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator.

R O Weinzierl1, B D Dynlacht, R Tjian.   

Abstract

The TFIID complex consists of the TATA-binding protein (TBP) and associated factors (TAFs) serving to mediate transcriptional activation by promoter-specific regulators. Here we report the cloning of Drosophila TAFII250 and the assembly of a partial complex containing recombinant TBP, TAFII110 and the C-terminal domain of TAFII250. This triple complex supports Sp1 activation and reveals specific interactions between TAFII250, TBP and TAFII110.

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Year:  1993        PMID: 8464492     DOI: 10.1038/362511a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  69 in total

1.  Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters.

Authors:  J M Park; B S Gim; J M Kim; J H Yoon; H S Kim; J G Kang; Y J Kim
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

2.  In vivo transcription factor recruitment during thyroid hormone receptor-mediated activation.

Authors:  M K Kim; J S Lee; J H Chung
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

3.  Requirement for TAF(II)250 acetyltransferase activity in cell cycle progression.

Authors:  E L Dunphy; T Johnson; S S Auerbach; E H Wang
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

4.  Sp1 binds to the precise locus of end processing within the terminal repeats of Epstein-Barr virus DNA.

Authors:  R Sun; T A Spain; S F Lin; G Miller
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

5.  Coactivator cross-talk specifies transcriptional output.

Authors:  Michael T Marr; Yoh Isogai; Kevin J Wright; Robert Tjian
Journal:  Genes Dev       Date:  2006-06-01       Impact factor: 11.361

6.  Requirement for transcription factor IIA (TFIIA)-TFIID recruitment by an activator depends on promoter structure and template competition.

Authors:  P M Lieberman; J Ozer; D B Gürsel
Journal:  Mol Cell Biol       Date:  1997-11       Impact factor: 4.272

7.  TAF7: a possible transcription initiation check-point regulator.

Authors:  Anne Gegonne; Jocelyn D Weissman; Meisheng Zhou; John N Brady; Dinah S Singer
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-09       Impact factor: 11.205

8.  Transcriptional corepression in vitro: a Mot1p-associated form of TATA-binding protein is required for repression by Leu3p.

Authors:  P A Wade; J A Jaehning
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

9.  TAF-like functions of human cytomegalovirus immediate-early proteins.

Authors:  D M Lukac; N Y Harel; N Tanese; J C Alwine
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

10.  Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly.

Authors:  P S Pendergrast; D Morrison; W P Tansey; N Hernandez
Journal:  J Virol       Date:  1996-08       Impact factor: 5.103

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