Literature DB >> 8462680

Metabolic channelling and control of the flux.

B N Kholodenko1, H V Westerhoff.   

Abstract

Metabolic control theory is extended to include channelled metabolism in general. A simple relationship between the flux control by the enzymes and the degree of metabolite channelling is derived. This relationship suggests experiments in which modulation of gene expression allows one to quantify channelling.

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Year:  1993        PMID： 8462680     DOI： 10.1016/0014-5793(93)81660-r

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  20 in total

1.  Metabolic control analysis under uncertainty: framework development and case studies.

Authors:  Liqing Wang; Inanç Birol; Vassily Hatzimanikatis
Journal:  Biophys J       Date:  2004-10-01       Impact factor: 4.033

2.  A model for protein translation: polysome self-organization leads to maximum protein synthesis rates.

Authors:  Hermioni Zouridis; Vassily Hatzimanikatis
Journal:  Biophys J       Date:  2006-11-10       Impact factor: 4.033

Review 3.  Computational biochemistry: systems biology minireview series.

Authors:  Ravi Iyengar
Journal:  J Biol Chem       Date:  2008-10-20       Impact factor: 5.157

4.  Comparative analysis of some aspects of mitochondrial metabolism in differentiated and undifferentiated neuroblastoma cells.

Authors:  Aleksandr Klepinin; Vladimir Chekulayev; Natalja Timohhina; Igor Shevchuk; Kersti Tepp; Andrus Kaldma; Andre Koit; Valdur Saks; Tuuli Kaambre
Journal:  J Bioenerg Biomembr       Date:  2013-09-27       Impact factor: 2.945

5.  Control of translation initiation: a model-based analysis from limited experimental data.

Authors:  Richard J Dimelow; Stephen J Wilkinson
Journal:  J R Soc Interface       Date:  2009-01-06       Impact factor: 4.118

6.  Control of respiration by cytochrome c oxidase in intact cells: role of the membrane potential.

Authors:  Maria Elena Dalmonte; Elena Forte; Maria Luisa Genova; Alessandro Giuffrè; Paolo Sarti; Giorgio Lenaz
Journal:  J Biol Chem       Date:  2009-09-23       Impact factor: 5.157

7.  Control theory of metabolic channelling.

Authors:  B N Kholodenko; M Cascante; H V Westerhoff
Journal:  Mol Cell Biochem       Date:  1995-02-23       Impact factor: 3.396

8.  Subtleties in control by metabolic channelling and enzyme organization.

Authors:  B N Kholodenko; J M Rohwer; M Cascante; H V Westerhoff
Journal:  Mol Cell Biochem       Date:  1998-07       Impact factor: 3.396

Review 9.  Elusive control.

Authors:  H V Westerhoff; B N Kholodenko; M Cascante; K Van Dam
Journal:  J Bioenerg Biomembr       Date:  1995-10       Impact factor: 2.945

Review 10.  Molecular and Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System: Implications for Pathology.

Authors:  Salvatore Nesci; Fabiana Trombetti; Alessandra Pagliarani; Vittoria Ventrella; Cristina Algieri; Gaia Tioli; Giorgio Lenaz
Journal:  Life (Basel)       Date:  2021-03-15
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