| Literature DB >> 8454909 |
G Harms1, K Zwingenberger, B Sandkamp, S Omena, C Pedrosa, J Richter, F Rosenkaimer, H Feldmeier, U Bienzle.
Abstract
The clinical, parasitological, hematological, and serological evolution of visceral leishmaniasis in Brazilian patients was assessed during treatment with human recombinant interferon-gamma (rIFN-gamma; 0.1 mg/m2 i.m. days 1-14) followed by pentavalent antimony (Sbv; 10 mg/kg days 22-28). At day 30, 6 patients had improved, 2 had slightly improved, and 1 patient had deteriorated. IFN-gamma was well tolerated in the dose tested and may be very effective as an adjunct to conventional therapy with antimony.Entities:
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Year: 1993 PMID: 8454909 DOI: 10.1089/jir.1993.13.39
Source DB: PubMed Journal: J Interferon Res ISSN: 0197-8357