Literature DB >> 8454370

Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis.

D P Nicolau1, C D Freeman, C H Nightingale, R Quintiliani, C J Coe, E G Maderazo, B W Cooper.   

Abstract

Using a rabbit model of Staphylococcus aureus endocarditis, we studied the effects of aspirin on the natural progression of this infection. Compared with untreated animals, the aspirin-treated animals showed a 30% (P = 0.11) reduction in the weight of the vegetations and an 84% (P = 0.03) reduction in the bacterial titer of the vegetations.

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Year:  1993        PMID： 8454370      PMCID： PMC281409          DOI： 10.1128/iai.61.4.1593-1595.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  In vitro correlation of platelet aggregation with occurrence of disseminated intravascular coagulation and subacute bacterial endocarditis.

Authors:  C M Kessler; E Nussbaum; C U Tuazon
Journal:  J Lab Clin Med       Date:  1987-06

2.  [Effect of various doses of aspirin on the development of aseptic thrombotic aortic endocarditis experimentally induced in the rabbit].

Authors:  R Pujadas; E Escrivá; F Fernández; J Jané; J Argimón; P Fava; M C Galera
Journal:  Rev Esp Cardiol       Date:  1988-01       Impact factor: 4.753

3.  Simultaneous measurements of acetaminophen and salicylate in plasma by liquid chromatography.

Authors:  J N Miceli; M K Aravind; S N Cohen; A K Done
Journal:  Clin Chem       Date:  1979-06       Impact factor: 8.327

4.  The enigma of aspirin.

Authors:  J D Parkin
Journal:  Aust N Z J Med       Date:  1987-04

Review 5.  Role of fibronectin in infective endocarditis.

Authors:  R J Hamill
Journal:  Rev Infect Dis       Date:  1987 Jul-Aug

6.  The effects of varying doses of aspirin on human platelet activation induced by PAF, collagen and arachidonic acid.

Authors:  M L Taylor; N L Misso; G A Stewart; P J Thompson
Journal:  Br J Clin Pharmacol       Date:  1992-01       Impact factor: 4.335

7.  Thrombospondin binds to Staphylococcus aureus and promotes staphylococcal adherence to surfaces.

Authors:  M Herrmann; S J Suchard; L A Boxer; F A Waldvogel; P D Lew
Journal:  Infect Immun       Date:  1991-01       Impact factor: 3.441

8.  Effect of aspirin on thrombogenesis and on production of experimental aortic valvular Streptococcus viridans endocarditis in rabbits.

Authors:  M E Levison; J Carrizosa; D Tanphaichitra; P K Schick; W Rubin
Journal:  Blood       Date:  1977-04       Impact factor: 22.113

9.  Comparative aspirin absorption kinetics after administration of sodium- and potassium-containing buffered solutions.

Authors:  W D Mason
Journal:  J Pharm Sci       Date:  1984-07       Impact factor: 3.534

10.  Experimental endocarditis I. Staphylococcal endocarditis in rabbits resulting from placement of a polyethylene catheter in the right side of the heart.

Authors:  P K Garrison; L R Freedman
Journal:  Yale J Biol Med       Date:  1970-06
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  21 in total

1.  Staphylococcus aureus, Platelets, and the Heart.

Authors: 
Journal:  Curr Infect Dis Rep       Date:  2000-08       Impact factor: 3.725

Review 2.  Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?

Authors:  David Brown
Journal:  Nat Rev Drug Discov       Date:  2015-10-23       Impact factor: 84.694

3.  Impact of antiplatelet therapy on clinical manifestations and outcomes of cardiovascular infections.

Authors:  Ammar Habib; Larry M Baddour; M Rizwan Sohail
Journal:  Curr Infect Dis Rep       Date:  2013-08       Impact factor: 3.725

4.  Clinical trial report: is it safe to continue anticoagulation therapy in patients with infective endocarditis?

Authors:  Donald P Levine
Journal:  Curr Infect Dis Rep       Date:  2010-07       Impact factor: 3.725

5.  Is there a role for antiplatelet therapy in infective endocarditis? A review of current scientific evidence.

Authors:  Nandan S Anavekar; Joseph G Murphy
Journal:  Curr Infect Dis Rep       Date:  2010-07       Impact factor: 3.725

6.  Platelets and Platelet Inhibitors in Infective Endocarditis.

Authors:  Bruno Hoen
Journal:  Curr Infect Dis Rep       Date:  2002-08       Impact factor: 3.725

7.  Staphylococcus aureus induces platelet aggregation via a fibrinogen-dependent mechanism which is independent of principal platelet glycoprotein IIb/IIIa fibrinogen-binding domains.

Authors:  A S Bayer; P M Sullam; M Ramos; C Li; A L Cheung; M R Yeaman
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

Review 8.  Salicylic acid: an old dog, new tricks, and staphylococcal disease.

Authors:  Mathias Herrmann
Journal:  J Clin Invest       Date:  2003-07       Impact factor: 14.808

9.  Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus.

Authors:  Leon Iri Kupferwasser; Michael R Yeaman; Cynthia C Nast; Deborah Kupferwasser; Yan-Qiong Xiong; Marco Palma; Ambrose L Cheung; Arnold S Bayer
Journal:  J Clin Invest       Date:  2003-07       Impact factor: 14.808

Review 10.  Platelets in defense against bacterial pathogens.

Authors:  Michael R Yeaman
Journal:  Cell Mol Life Sci       Date:  2009-12-15       Impact factor: 9.261
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