Literature DB >> 445799

Simultaneous measurements of acetaminophen and salicylate in plasma by liquid chromatography.

J N Miceli, M K Aravind, S N Cohen, A K Done.   

Abstract

We describe a "highly-performance" liquid chromatographic method in which 8-chlorotheophylline is used as an internal standard to determine acetaminophen and salicylate simultaneously in plasma samples. Therapeutic as well as toxic concentrations can be determined on samples as small as 50 micro L, which makes the method particularly useful for determinations on samples from young children. The procedure requires a simple extraction of the drugs, and the chromatography is completed in 6 min.

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Year:  1979        PMID： 445799

Source DB:  PubMed          Journal:  Clin Chem        ISSN： 0009-9147            Impact factor:   8.327


  7 in total

1.  Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes.

Authors:  Emilie Bahne; Emily W L Sun; Richard L Young; Morten Hansen; David P Sonne; Jakob S Hansen; Ulrich Rohde; Alice P Liou; Margaret L Jackson; Dayan de Fontgalland; Philippa Rabbitt; Paul Hollington; Luigi Sposato; Steven Due; David A Wattchow; Jens F Rehfeld; Jens J Holst; Damien J Keating; Tina Vilsbøll; Filip K Knop
Journal:  JCI Insight       Date:  2018-12-06

2.  Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis.

Authors:  D P Nicolau; C D Freeman; C H Nightingale; R Quintiliani; C J Coe; E G Maderazo; B W Cooper
Journal:  Infect Immun       Date:  1993-04       Impact factor: 3.441

Review 3.  Drug interferences with plasma assays in therapeutic drug monitoring.

Authors:  S Yosselson-Superstine
Journal:  Clin Pharmacokinet       Date:  1984 Jan-Feb       Impact factor: 6.447

4.  Salicylate and acetaminophen in donated blood.

Authors:  A MacIntyre; J D Gray; M Gorelick; K Renton
Journal:  CMAJ       Date:  1986-08-01       Impact factor: 8.262

5.  Effect of migraine attacks on paracetamol absorption.

Authors:  R A Tokola; P J Neuvonen
Journal:  Br J Clin Pharmacol       Date:  1984-12       Impact factor: 4.335

6.  Characterisation of oral and i.v. glucose handling in truncally vagotomised subjects with pyloroplasty.

Authors:  Astrid Plamboeck; Simon Veedfald; Carolyn F Deacon; Bolette Hartmann; André Wettergren; Lars B Svendsen; Søren Meisner; Claus Hovendal; Filip K Knop; Tina Vilsbøll; Jens J Holst
Journal:  Eur J Endocrinol       Date:  2013-07-06       Impact factor: 6.664

7.  Effects of liraglutide on gallbladder emptying: A randomized, placebo-controlled trial in adults with overweight or obesity.

Authors:  Christina C Nexøe-Larsen; Pernille H Sørensen; Helene Hausner; Mikkel Agersnap; Mille Baekdal; Andreas Brønden; Lea N Gustafsson; David P Sonne; Louise Vedtofte; Tina Vilsbøll; Filip K Knop
Journal:  Diabetes Obes Metab       Date:  2018-07-10       Impact factor: 6.577
  7 in total

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