Literature DB >> 8450754

Molecular evolution of a repetitive region within the per gene of Drosophila.

A A Peixoto1, S Campesan, R Costa, C P Kyriacou.   

Abstract

The clock gene period (per) controls a number of biological rhythms in Drosophila. In D. melanogaster, per has a repetitive region that encodes a number of alternating threonine-glycine residues. We sequenced and compared this region from several different Drosophila species belonging to various groups within the Drosophila and Sophophora subgenera. This part of per shows a great variability in both DNA sequence and length. Furthermore, analysis of the data suggests that changes in the length of this variable region might be associated with amino acid replacements in the more conserved flanking sequences.

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Year:  1993        PMID: 8450754     DOI: 10.1093/oxfordjournals.molbev.a039993

Source DB:  PubMed          Journal:  Mol Biol Evol        ISSN: 0737-4038            Impact factor:   16.240


  17 in total

1.  Different period gene repeats take 'turns' at fine-tuning the circadian clock.

Authors:  V Guantieri; A Pepe; M Zordan; C P Kyriacou; R Costa; A M Tamburro
Journal:  Proc Biol Sci       Date:  1999-11-22       Impact factor: 5.349

Review 2.  Flies, clocks and evolution.

Authors:  E Rosato; C P Kyriacou
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-11-29       Impact factor: 6.237

3.  Population genetics of the developmental gene optomotor-blind (omb) in Drosophila polymorpha: evidence for a role in abdominal pigmentation variation.

Authors:  Jennifer A Brisson; Alan R Templeton; Ian Duncan
Journal:  Genetics       Date:  2004-12       Impact factor: 4.562

4.  The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis.

Authors:  J M Andreoli; S I Jang; E Chung; C M Coticchia; P M Steinert; N G Markova
Journal:  Nucleic Acids Res       Date:  1997-11-01       Impact factor: 16.971

5.  Conceptual translation of timeless reveals alternative initiating methionines in Drosophila.

Authors:  E Rosato; A Trevisan; F Sandrelli; M Zordan; C P Kyriacou; R Costa
Journal:  Nucleic Acids Res       Date:  1997-02-01       Impact factor: 16.971

6.  Comparative analysis of the nonA region in Drosophila identifies a highly diverged 5' gene that may constrain nonA promoter evolution.

Authors:  S Campesan; D Chalmers; F Sandrelli; A Megighian; A A Peixoto; R Costa; C P Kyriacou
Journal:  Genetics       Date:  2001-02       Impact factor: 4.562

Review 7.  The overdue promise of short tandem repeat variation for heritability.

Authors:  Maximilian O Press; Keisha D Carlson; Christine Queitsch
Journal:  Trends Genet       Date:  2014-08-30       Impact factor: 11.639

8.  Drive-selection equilibrium: homopolymer evolution in the Drosophila gene mastermind.

Authors:  S J Newfeld; H Tachida; B Yedvobnick
Journal:  J Mol Evol       Date:  1994-06       Impact factor: 2.395

9.  The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae.

Authors:  K Mitsui; S Yaguchi; K Tsurugi
Journal:  Mol Cell Biol       Date:  1994-08       Impact factor: 4.272

10.  Mutational mechanisms, phylogeny, and evolution of a repetitive region within a clock gene of Drosophila melanogaster.

Authors:  E Rosato; A A Peixoto; A Gallippi; C P Kyriacou; R Costa
Journal:  J Mol Evol       Date:  1996-04       Impact factor: 2.395

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