Literature DB >> 8448262

Brain lithium concentrations measured with lithium-7 magnetic resonance spectroscopy in patients with affective disorders: relationship to erythrocyte and serum concentrations.

T Kato1, T Shioiri, T Inubushi, S Takahashi.   

Abstract

Brain lithium concentrations were measured in eight patients with affective disorders using lithium-7 magnetic resonance spectroscopy (MRS). Brain lithium concentrations correlated better with serum concentrations (n = 23, r = 0.66, p < 0.001) than with erythrocyte concentrations (r = 0.44, p < 0.05). Because of previous data in animal experiments these results were unexpected, but the differences in cation transport mechanisms between neurons and erythrocytes may account for the results.

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Year:  1993        PMID： 8448262     DOI： 10.1016/0006-3223(93)90133-x

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN： 0006-3223            Impact factor:   13.382


  7 in total

1.  Twelve-hour brain lithium concentration in lithium maintenance treatment of manic-depressive disorder: daily versus alternate-day dosing schedule.

Authors:  H V Jensen; P Plenge; A Stensgaard; E T Mellerup; C Thomsen; H Aggernaes; O Henriksen
Journal:  Psychopharmacology (Berl)       Date:  1996-04       Impact factor: 4.530

Review 2.  Metabolism and excretion of mood stabilizers and new anticonvulsants.

Authors:  T A Ketter; M A Frye; G Corá-Locatelli; T A Kimbrell; R M Post
Journal:  Cell Mol Neurobiol       Date:  1999-08       Impact factor: 5.046

Review 3.  Lithium in bipolar disorder: can drug concentrations predict therapeutic effect?

Authors:  Beth Sproule
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

4.  BDNF protein levels are decreased in transformed lymphoblasts from lithium-responsive patients with bipolar disorder.

Authors:  Michael Tseng; Martin Alda; Li Xu; Xiujun Sun; Jun-Feng Wang; Paul Grof; Gustavo Turecki; Guy Rouleau; L Trevor Young
Journal:  J Psychiatry Neurosci       Date:  2008-09       Impact factor: 6.186

5.  Mesocortical BDNF signaling mediates antidepressive-like effects of lithium.

Authors:  Di Liu; Qian-Qian Tang; Di Wang; Su-Pei Song; Xiao-Na Yang; Su-Wan Hu; Zhi-Yong Wang; Zheng Xu; He Liu; Jun-Xia Yang; Sarah E Montgomery; Hongxing Zhang; Ming-Hu Han; Hai-Lei Ding; Jun-Li Cao
Journal:  Neuropsychopharmacology       Date:  2020-05-19       Impact factor: 7.853

Review 6.  Neurochemical predictors of response to pharmacologic treatments for bipolar disorder.

Authors:  Melissa P Delbello; Stephen M Strakowski
Journal:  Curr Psychiatry Rep       Date:  2004-12       Impact factor: 8.081

Review 7.  The Role of Mitonuclear Incompatibility in Bipolar Disorder Susceptibility and Resilience Against Environmental Stressors.

Authors:  Suzanne Gonzalez
Journal:  Front Genet       Date:  2021-03-16       Impact factor: 4.599
  7 in total

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