Literature DB >> 844565

Induction of an intestinal epithelial sugar transport system by high blood sugar.

T Z Csáky, E Fischer.   

Abstract

Intravenous infusion of glucose produces a marked increase of the mucosal-to-serosal sugar flux in the isolated everted small intestine of rats. The phenomenon is partially substrate specific, is inhibited by phloretin but not by phlorizin and is completely abolished by cycloheximide. The results suggest that sustained hyperglycemia may stimulate the synthesis of new transport receptors (carriers).

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Year:  1977        PMID： 844565     DOI： 10.1007/BF02124079

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  An effect of alloxan-diabetes on the active transport of sugars by rat small intestine, in vitro.

Authors:  R K CRANE
Journal:  Biochem Biophys Res Commun       Date:  1961-04-28       Impact factor: 3.575

2.  Intestinal transport of 3-O-methyl-D-glucose in the normal and alloxan-diabetic rat.

Authors:  P Flores; H P Schedl
Journal:  Am J Physiol       Date:  1968-04

3.  Insulin stimulated transport of 3-O- methyl glucose across the rat jejunum.

Authors:  R S Dubois; C C Roy
Journal:  Proc Soc Exp Biol Med       Date:  1969-03

4.  Intestinal transport of glucose and sodium: changes in alloxan diabetes and effects of insulin.

Authors:  K A Aulsebrook
Journal:  Experientia       Date:  1965-06-15

5.  Intestinal transport of sugars and amino acids in diabetic rats.

Authors:  W A Olsen; I H Rosenberg
Journal:  J Clin Invest       Date:  1970-01       Impact factor: 14.808
  5 in total
  6 in total

1.  Hyperglycemia and net transintestinal glucose and sodium transport in the rat.

Authors:  G Esposito; A Faelli; M Tosco; V Capraro
Journal:  Pflugers Arch       Date:  1981-05       Impact factor: 3.657

2.  Effect of sodium concentration and plasma sugar concentration on hexose absorption by the rat jejunum in vivo. Further evidence of two transport mechanisms.

Authors:  E S Debnam
Journal:  Pflugers Arch       Date:  1982-03       Impact factor: 3.657

Review 3.  Upper gastrointestinal function and glycemic control in diabetes mellitus.

Authors:  Reawika Chaikomin; Christopher K Rayner; Karen-L Jones; Michael Horowitz
Journal:  World J Gastroenterol       Date:  2006-09-21       Impact factor: 5.742

4.  Factors affecting the utilization of ketone bodies and other substrates by rat jejunum: effects of fasting and of diabetes.

Authors:  P J Hanson; D S Parsons
Journal:  J Physiol       Date:  1978-05       Impact factor: 5.182

5.  Quantitative study of mucosal structure, enzyme activities and phenylalanine accumulation in jejunal biopsies of patients with early and late onset diabetes.

Authors:  E O Riecken; A Zennek; A Lay; H Menge
Journal:  Gut       Date:  1979-11       Impact factor: 23.059

6.  Effect of hyperglycaemia on sugar transport in the isolated mucosa of guinea-pig small intestine.

Authors:  E Fischer; F Lauterbach
Journal:  J Physiol       Date:  1984-10       Impact factor: 5.182
  6 in total

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