Literature DB >> 8444788

Regulation of pyocin genes in Pseudomonas aeruginosa by positive (prtN) and negative (prtR) regulatory genes.

H Matsui1, Y Sano, H Ishihara, T Shinomiya.   

Abstract

Most strains of Pseudomonas aeruginosa produce various types of bacteriocins (pyocins), namely, R-, F-, and S-type pyocins. The production of all types of pyocins was shown to be regulated by positive (prtN) and negative (prtR) regulatory genes. The prtN gene activates the expression of various pyocin genes, probably by the interaction of its product with the DNA sequences conserved in the 5' noncoding regions of the pyocin genes. The prtR gene represses the expression of the prtN gene, and its product, predicted from the nucleotide sequence, has a structure characteristic of phage repressors and seems to be inactivated by the RecA protein activated by DNA damage. A model for the regulation of the pyocin genes is proposed.

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Year:  1993        PMID: 8444788      PMCID: PMC193209          DOI: 10.1128/jb.175.5.1257-1263.1993

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  24 in total

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Journal:  Gene       Date:  1981-12       Impact factor: 3.688

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Authors:  Y Sano; M Kageyama
Journal:  J Bacteriol       Date:  1984-05       Impact factor: 3.490

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  58 in total

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7.  Determination of DNA sequences required for regulated Mycobacterium tuberculosis RecA expression in response to DNA-damaging agents suggests that two modes of regulation exist.

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Journal:  J Bacteriol       Date:  1997-06       Impact factor: 3.490

8.  Pseudomonas chlororaphis Produces Multiple R-Tailocin Particles That Broaden the Killing Spectrum and Contribute to Persistence in Rhizosphere Communities.

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9.  PtrB of Pseudomonas aeruginosa suppresses the type III secretion system under the stress of DNA damage.

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10.  Plant lectin-like bacteriocin from a rhizosphere-colonizing Pseudomonas isolate.

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Journal:  J Bacteriol       Date:  2003-02       Impact factor: 3.490

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