Literature DB >> 8444693

Changes in regional blood flow distribution and oxygen supply during hypoxia in conscious rats.

I Kuwahira1, N C Gonzalez, N Heisler, J Piiper.   

Abstract

The effects of acute hypoxia on central hemodynamics, regional blood flow, and regional oxygen supply (blood flow x arterial O2 concentration) were studied in conscious resting rats. Regional blood flow was determined by the radiolabeled microsphere technique. Blood pressure, heart rate; and aortic blood flow increased and total peripheral resistance decreased significantly during hypoxia. Blood flow to brain, respiratory muscles, and liver increased both in absolute value and as a fraction of the aortic blood flow. Fractional blood flow to the gastrointestinal tract, spleen, pancreas, skin, fat, and hindlimb bones decreased during hypoxia; blood flow decreased in absolute values only in stomach and fat. Oxygen supply to brain, respiratory muscles, and liver increased during hypoxia, whereas it decreased in the remaining organs investigated.

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Year:  1993        PMID： 8444693     DOI： 10.1152/jappl.1993.74.1.211

Source DB:  PubMed          Journal:  J Appl Physiol (1985)        ISSN： 0161-7567


  14 in total

1.  Acute hypoxia induces hypertriglyceridemia by decreasing plasma triglyceride clearance in mice.

Authors:  Jonathan C Jun; Mi-Kyung Shin; Qiaoling Yao; Shannon Bevans-Fonti; James Poole; Luciano F Drager; Vsevolod Y Polotsky
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-05-22       Impact factor: 4.310

2.  Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy.

Authors:  Jonathan C Jun; Mi-Kyung Shin; Ronald Devera; Qiaoling Yao; Omar Mesarwi; Shannon Bevans-Fonti; Vsevolod Y Polotsky
Journal:  Am J Physiol Endocrinol Metab       Date:  2014-10-14       Impact factor: 4.310

Review 3.  The physiology of a local renin-angiotensin system in the pancreas.

Authors:  Po Sing Leung
Journal:  J Physiol       Date:  2007-01-11       Impact factor: 5.182

4.  Quantitative blood flow measurements in the small animal cardiopulmonary system using digital subtraction angiography.

Authors:  MingDe Lin; Craig T Marshall; Yi Qi; Samuel M Johnston; Cristian T Badea; Claude A Piantadosi; G Allan Johnson
Journal:  Med Phys       Date:  2009-11       Impact factor: 4.071

5.  The effect of short-term hypoxic exposure on metabolic gene expression.

Authors:  Meredith V Everett; Corina E Antal; Douglas L Crawford
Journal:  J Exp Zool A Ecol Genet Physiol       Date:  2011-10-21

6.  Estimation of jugular venous O2 saturation from cerebral oximetry or arterial O2 saturation during isocapnic hypoxia.

Authors:  M B Kim; D S Ward; C R Cartwright; J Kolano; S Chlebowski; L C Henson
Journal:  J Clin Monit Comput       Date:  2000       Impact factor: 2.502

7.  Thermoneutrality modifies the impact of hypoxia on lipid metabolism.

Authors:  Jonathan C Jun; Mi-Kyung Shin; Qiaoling Yao; Ronald Devera; Shannon Fonti-Bevans; Vsevolod Y Polotsky
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-12-18       Impact factor: 4.310

8.  Epidermal sensing of oxygen is essential for systemic hypoxic response.

Authors:  Adam T Boutin; Alexander Weidemann; Zhenxing Fu; Lernik Mesropian; Katarina Gradin; Colin Jamora; Michael Wiesener; Kai-Uwe Eckardt; Cameron J Koch; Lesley G Ellies; Gabriel Haddad; Volker H Haase; M Celeste Simon; Lorenz Poellinger; Frank L Powell; Randall S Johnson
Journal:  Cell       Date:  2008-04-18       Impact factor: 41.582

9.  Impaired vasoconstriction and nitric oxide-mediated relaxation in pulmonary arteries of hypoxia- and monocrotaline-induced pulmonary hypertensive rats.

Authors:  Virak Mam; Alain F Tanbe; Sally H Vitali; Elena Arons; Helen A Christou; Raouf A Khalil
Journal:  J Pharmacol Exp Ther       Date:  2009-11-13       Impact factor: 4.030

10.  Effects of acute hypoxia on left and right ventricular contractility in chronic obstructive pulmonary disease.

Authors:  Ferit Akgül; Talantbek Batyraliev; Zarema Karben; Igor Pershukov
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2007
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