B A Kingwell1, G L Jennings. 1. Alfred and Baker Medical Unit, Baker Medical Research Institute, Prahran, VIC.
Abstract
OBJECTIVE: Rational use of non-pharmacological therapy for elevated blood pressure requires some knowledge of dose-effect relationships to optimise regimens. We investigated the effects on blood pressure of: one hour of walking at 50% of predetermined maximal work capacity (Wmax); 15 minutes of cycling at 80%-90% of Wmax (high-intensity cycling; HIC)--each performed five days per week; and three 30-minute cycling sessions per week at 65%-70% of Wmax (moderate-intensity cycling; MIC) which we have previously found lowers blood pressure in both normotensive and hypertensive people. DESIGN: The three exercise interventions and a period of normal sedentary activity were performed for four weeks each, by 14 normotensive volunteers (seven male, seven female) in a randomised 4 x 4 Latin-square design. RESULTS: MIC produced the greatest blood pressure reduction relative to the period of normal sedentary activity--mean 5/3 mmHg; standard error of the difference (SE-diff) 2/1 mmHg; P < 0.05 in the supine position, and 4/5 mmHg; SE-diff 2/2 mmHg; P < 0.05 standing. Walking induced smaller blood pressure reductions--3/2 mmHg; SE-diff, 2/1 mmHg (P < 0.05 for systolic pressure), and 2/1 mmHg; SE-diff, 2/2 mmHg for the supine and standing positions, respectively. The HIC did not change blood pressure. Heart rate reduction with training was proportional to exercise intensity. Cardiac output, body weight, 24-hour urinary sodium excretion, cholesterol and triglyceride levels did not alter with any of the interventions. CONCLUSIONS: Effects of exercise on blood pressure vary according to the intensity and duration of training bouts. Moderate exercise levels may be optimal, but walking is also effective.
RCT Entities:
OBJECTIVE: Rational use of non-pharmacological therapy for elevated blood pressure requires some knowledge of dose-effect relationships to optimise regimens. We investigated the effects on blood pressure of: one hour of walking at 50% of predetermined maximal work capacity (Wmax); 15 minutes of cycling at 80%-90% of Wmax (high-intensity cycling; HIC)--each performed five days per week; and three 30-minute cycling sessions per week at 65%-70% of Wmax (moderate-intensity cycling; MIC) which we have previously found lowers blood pressure in both normotensive and hypertensivepeople. DESIGN: The three exercise interventions and a period of normal sedentary activity were performed for four weeks each, by 14 normotensive volunteers (seven male, seven female) in a randomised 4 x 4 Latin-square design. RESULTS: MIC produced the greatest blood pressure reduction relative to the period of normal sedentary activity--mean 5/3 mmHg; standard error of the difference (SE-diff) 2/1 mmHg; P < 0.05 in the supine position, and 4/5 mmHg; SE-diff 2/2 mmHg; P < 0.05 standing. Walking induced smaller blood pressure reductions--3/2 mmHg; SE-diff, 2/1 mmHg (P < 0.05 for systolic pressure), and 2/1 mmHg; SE-diff, 2/2 mmHg for the supine and standing positions, respectively. The HIC did not change blood pressure. Heart rate reduction with training was proportional to exercise intensity. Cardiac output, body weight, 24-hour urinary sodium excretion, cholesterol and triglyceride levels did not alter with any of the interventions. CONCLUSIONS: Effects of exercise on blood pressure vary according to the intensity and duration of training bouts. Moderate exercise levels may be optimal, but walking is also effective.
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