Literature DB >> 8425651

Effects of pentoxifylline on sperm motility and hyperactivated motility in vitro: a preliminary report.

S C Pang1, D B Williams, T Huang, C Wang.   

Abstract

Previous reports (2, 3) have suggested that pentoxifylline increases sperm motility. In this preliminary report based on five asthenozoospermic and five normal motility semen samples, we were unable to demonstrate any statistically significant effect of pentoxifylline on percent motility of human spermatozoa. However, in vitro exposure to capacitation medium with pentoxifylline may lead to an increase in total hyperactivated motility in asthenozoospermic samples, an effect not evident in the normal motility samples in this study.

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Year:  1993        PMID： 8425651

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  4 in total

1.  An evaluation of the effect of pentoxifylline on sperm function and treatment outcome of male-factor infertility: a preliminary study.

Authors:  S Fountain; B Rizk; S Avery; C Palmer; M Blayney; M Macnamee; C Mills; P Brinsden
Journal:  J Assist Reprod Genet       Date:  1995-11       Impact factor: 3.412

2.  Successful use of pentoxifylline in male-factor infertility and previous failure of in vitro fertilization: a prospective randomized study.

Authors:  B Rizk; S Fountain; S Avery; C Palmer; M Blayney; M Macnamee; C Mills; P Brinsden
Journal:  J Assist Reprod Genet       Date:  1995-11       Impact factor: 3.412

3.  Effects of pentoxifylline on human sperm parameters in vitro.

Authors:  I Mladenovic; S Micic; R M Pearson; O Genbacev; N Papic
Journal:  J Assist Reprod Genet       Date:  1994-11       Impact factor: 3.412

Review 4.  Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review.

Authors:  Yi Lu; Hao Su; Jianzhong Zhang; Yutao Wang; Hongjun Li
Journal:  Front Pharmacol       Date:  2022-01-12       Impact factor: 5.810
  4 in total

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