PURPOSE: Pentoxifylline was tested in three raising concentrations (0.7 mM/l, 1.5 mM/l, 3.6 mM/l) on human sperm cells in vitro. METHODS: On 143 samples, we examined drug effect on motile sperm concentration, grade of their motility, acrosome reaction and membrane status. RESULTS: Obtained results show improvement in motile sperm concentration, as well as in the grade of progression in the majority of samples. CONCLUSIONS: Spermatozoa membranes as well as occurrence of the acrosomal reaction were not affected by pentoxifylline.
PURPOSE:Pentoxifylline was tested in three raising concentrations (0.7 mM/l, 1.5 mM/l, 3.6 mM/l) on human sperm cells in vitro. METHODS: On 143 samples, we examined drug effect on motile sperm concentration, grade of their motility, acrosome reaction and membrane status. RESULTS: Obtained results show improvement in motile sperm concentration, as well as in the grade of progression in the majority of samples. CONCLUSIONS: Spermatozoa membranes as well as occurrence of the acrosomal reaction were not affected by pentoxifylline.