| Literature DB >> 8419730 |
N W Lutz1, A C Kuesel, W E Hull.
Abstract
This report describes a noninvasive 1H-NMR method for measuring absolute temperatures (+/- 0.2 degrees C) in biological samples and, in particular, in cell culture perfusion systems, utilizing the linear temperature dependence of the water chemical shift relative to the temperature-independent shift of one of the components of the biological medium, e.g., pyruvate, acetate or lactate. The effects of flow on temperature can be monitored and appropriate adjustment of the temperature controller can be made.Entities:
Mesh:
Year: 1993 PMID: 8419730 DOI: 10.1002/mrm.1910290120
Source DB: PubMed Journal: Magn Reson Med ISSN: 0740-3194 Impact factor: 4.668