Literature DB >> 8414567

A comparison of growth rates of acoustic neuromas: nonsurgical patients vs. subtotal resection.

S I Rosenberg1, H Silverstein, M A Gordon, J M Flanzer, T O Willcox, J Silverstein.   

Abstract

A conservative approach to the management of acoustic neuromas in elderly patients has been used since 1971. Elderly patients without symptoms of brain stem compression are initially treated by observation and yearly radiographic imaging. A translabyrinthine radical-subtotal resection is performed if brain stem compression is present or if tumor is growing rapidly. Twenty-three patients, ages 65 to 86 years, had initial nonsurgical management of their tumors. Growth rates could be determined for 16 patients. Thirteen patients not requiring surgery had an average tumor growth rate of 0.6 mm/yr. Three patients with an average growth rate of 6.8 mm/yr eventually required surgery. No patient whose tumor was < 15 mm at initial evaluation has experienced brain stem symptoms or demonstrated rapid tumor growth. Twenty-four patients ages 65 to 86 years underwent planned subtotal tumor excision. Eighteen patients followed postoperatively for more than 1 year demonstrated an average rate of regrowth of tumor of 0.7 mm/yr.

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Year:  1993        PMID: 8414567     DOI: 10.1177/019459989310900316

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  5 in total

1.  Fast-growing vestibular schwannoma.

Authors:  M Falcioni; A Taibah; G De Donato; E Piccirillo; A Russo; M Sanna
Journal:  Skull Base Surg       Date:  2000

Review 2.  Methodological issues in longitudinal studies: vestibular schwannoma growth rates in neurofibromatosis 2.

Authors:  M E Baser; V-F Mautner; D M Parry; D G R Evans
Journal:  J Med Genet       Date:  2005-04-14       Impact factor: 6.318

3.  Surgical management of vestibular schwannoma in elderly patients.

Authors:  Amjad Nuseir; Giuliano Sequino; Giuseppe De Donato; Abdelkader Taibah; Mario Sanna
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-03-24       Impact factor: 2.503

4.  Conservative management of acoustic neuroma.

Authors:  Abdulrahman Al Sanosi; Paul A Fagan; Nigel D W Biggs
Journal:  Skull Base       Date:  2006-05

5.  Multifactor Influences of Shared Decision-Making in Acoustic Neuroma Treatment.

Authors:  Jason C Nellis; Jeff D Sharon; Seth E Pross; Lisa E Ishii; Masaru Ishii; Jacob K Dey; Howard W Francis
Journal:  Otol Neurotol       Date:  2017-03       Impact factor: 2.311

  5 in total

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