Literature DB >> 8405408

Widespread distribution of free D-aspartate in rat periphery.

A Hashimoto1, T Nishikawa, T Oka, T Hayashi, K Takahashi.   

Abstract

We have identified and quantified free D-aspartate in adult rat peripheral organs using gas chromatographic-mass spectrometric and high-performance liquid chromatographic techniques. The level of free D-aspartate was highest in the adrenal, testis, spleen and pituitary, followed by the thymus, lung, ovary, placenta, pancreas and heart, and below the detection limit in the kidney, liver, brain, muscle and serum. These data provide the first evidence that a high level of free D-aspartate widely occurs in the adult rat periphery and suggest that the D-amino acid may be an endogenous substrate for D-aspartate oxidase.

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Year:  1993        PMID： 8405408     DOI： 10.1016/0014-5793(93)80286-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  12 in total

1.  D-aspartate localizations imply neuronal and neuroendocrine roles.

Authors:  M J Schell; O B Cooper; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

2.  Crystallization and preliminary crystallographic analysis of D-aspartate oxidase from porcine kidney.

Authors:  Miki Senda; Atsushi Yamamoto; Hiroyuki Tanaka; Tetsuo Ishida; Kihachiro Horiike; Toshiya Senda
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2012-05-22

3.  D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.

Authors:  J P Mothet; A T Parent; H Wolosker; R O Brady; D J Linden; C D Ferris; M A Rogawski; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-25       Impact factor: 11.205

4.  Cephalopod vision involves dicarboxylic amino acids: D-aspartate, L-aspartate and L-glutamate.

Authors:  Salvatore D'Aniello; Patrizia Spinelli; Gabriele Ferrandino; Kevin Peterson; Mara Tsesarskia; George Fisher; Antimo D'Aniello
Journal:  Biochem J       Date:  2005-03-01       Impact factor: 3.857

5.  C-terminal tripeptide Ser-Asn-Leu (SNL) of human D-aspartate oxidase is a functional peroxisome-targeting signal.

Authors:  L Amery; C Brees; M Baes; C Setoyama; R Miura; G P Mannaerts; P P Van Veldhoven
Journal:  Biochem J       Date:  1998-12-01       Impact factor: 3.857

6.  Synaptic vesicular localization and exocytosis of L-aspartate in excitatory nerve terminals: a quantitative immunogold analysis in rat hippocampus.

Authors:  V Gundersen; F A Chaudhry; J G Bjaalie; F Fonnum; O P Ottersen; J Storm-Mathisen
Journal:  J Neurosci       Date:  1998-08-15       Impact factor: 6.167

7.  Differential effects of glutamate agonists and D-aspartate on oxytocin release from hypothalamus and posterior pituitary of male rats.

Authors:  M Pampillo; M del Carmen Díaz; B H Duvilanski; V Rettori; A Seilicovich; M Lasaga
Journal:  Endocrine       Date:  2001-08       Impact factor: 3.925

8.  Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study.

Authors:  Juan Pascual-Anaya; Salvatore D'Aniello
Journal:  Int J Biol Sci       Date:  2006-04-10       Impact factor: 6.580

Review 9.  The putative effects of D-Aspartic acid on blood testosterone levels: A systematic review.

Authors:  Farzad Roshanzamir; Seyyed Morteza Safavi
Journal:  Int J Reprod Biomed       Date:  2017-01

10.  Simultaneous Measurement of Amino Acid Enantiomers in Aged Mouse Brain Samples by LC/MS/MS Combined with Derivatization Using Nzzm321990 α-(5-Fluoro-2,4-dinitrophenyl)-l-leucinamide (l-FDLA).

Authors:  Taiji Yamamoto; Keisuke Yaku; Takashi Nakagawa
Journal:  Metabolites       Date:  2021-01-15
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